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Articles Published Processes
9/17/2026 5:48:21 AM | Browse: 0 | Download: 0
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Received |
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2026-05-25 08:38 |
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Peer-Review Started |
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2026-05-25 08:39 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-07-15 02:17 |
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Revised |
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2026-07-21 06:02 |
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Publication Fee Transferred |
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2026-07-30 00:07 |
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Second Decision by Editor |
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2026-08-28 02:55 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-08-28 09:22 |
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Articles in Press |
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2026-08-28 09:22 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-09-02 01:01 |
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Publish the Manuscript Online |
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2026-09-17 05:48 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Analysis of risk factors and a prediction model for rebleeding in liver cirrhosis patients with esophagogastric variceal bleeding
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ping-Ping Li, Xiao Zhong, Da-Ya Zhang and Fei-Hu Bai |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the 2025 Hainan Flexible Talent Introduction and Innovation Platform Performance Assessment; the Academic Improvement Support Program of Hainan Medical University |
No. XSTS2025001 and No. XSTS2026051 |
| Funded Project of the 2026 Undergraduate Scientific Research and Innovation Training Program, Hainan Medical University |
No. RZ2600001129 |
| the National Clinical Key Specialty Capacity Building Project |
No. 202330 |
| Hainan Provincial Education Reform Project |
No. hnjg2024-67 |
| the Joint Scientific and Technological Innovation Project of Health Commission of Hainan Province |
No. SQ2023WSJK0301 |
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| Corresponding Author |
Fei-Hu Bai, Chief Physician, Department of Gastroenterology, The Second Affiliated Hospital of Hainan Medical University, No. 368 Yehai Avenue, Longhua District, Haikou 570216, Hainan Province, China. hy214654@muhn.edu.cn |
| Key Words |
Liver cirrhosis; Esophageal and gastric varices; Esophagogastric variceal rebleeding; Prediction model |
| Core Tip |
This single-center retrospective study enrolled 130 cirrhotic patients with esophagogastric variceal bleeding (EGVB) in 2024 and conducted a one-year follow-up, including 62 rebleeding cases and 68 non-rebleeding cases, aiming to address the high mortality of EGVB rebleeding and the lack of simple non-invasive predictive tools for Hainan population. The study identified four independent risk factors for rebleeding -decreased red blood cell, elevated blood urea nitrogen, ascites, and thickening of the gallbladder wall (TGBW); notably, TGBW was originally validated as a novel non-invasive imaging predictor with an odds ratio value of 0.199 (P < 0.001). A reliable nomogram prediction model was further constructed with an original area under the curve (AUC) of 0.853 and a bootstrap internal validation AUC of 0.855, presenting favorable calibration and clinical applicability. Since this model merely requires routine blood tests and ultrasonic indicators, it can realize convenient and non-invasive risk stratification to guide secondary clinical prevention for local patients. Nevertheless, this research is limited by its retrospective nature, single-center setting and relatively small sample size; and further multi-center prospective studies are required to verify the generalizability of the model. |
| Publish Date |
2026-09-17 05:48 |
| Citation |
Li PP, Zhong X, Zhang DY, Bai FH. Analysis of risk factors and a prediction model for rebleeding in liver cirrhosis patients with esophagogastric variceal bleeding. World J Hepatol 2026; 18(9): 123456
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| URL |
https://www.wjgnet.com/1948-5182/full/v18/i9/123456.htm |
| DOI |
https://doi.org/10.4254/wjh.123456 |
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