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Articles Published Processes
12/2/2015 11:58:00 AM | Browse: 903 | Download: 1377
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Received |
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2014-07-04 09:04 |
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Peer-Review Started |
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2014-07-04 14:23 |
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To Make the First Decision |
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2014-07-29 11:57 |
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Return for Revision |
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2014-08-11 11:09 |
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Revised |
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2014-10-30 07:03 |
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Second Decision |
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2015-02-27 09:24 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2015-03-09 16:40 |
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Articles in Press |
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2015-03-09 16:40 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-05-15 14:27 |
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Publish the Manuscript Online |
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2015-05-19 17:49 |
| ISSN |
2220-3176 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Review |
| Article Title |
Treatment of methicillin-resistant Staphylococcus aureus infections: Importance of high vancomycin minumum inhibitory concentrations
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Alejandra Morales-Cartagena, Antonio Lalueza, Francisco López-Medrano, Rafael San Juan and José María Aguado |
| Funding Agency and Grant Number |
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| Corresponding Author |
Dr. Alejandra Morales-Cartagena, Infectious Diseases Unit, Department of Medicine, University Hospital 12 de Octubre, Av. Córdoba km 5.400, 28041 Madrid,
Spain. a.morales.cartagena@gmail.com
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| Key Words |
Staphylococcus aureus; Minimum inhibitory concentration; Methicillin-resistant Staphylococcus aureus; Vancomycin-intermediate Staphylococcus aureus; Heteroresistant-vancomycin-intermediate Staphylococcus aureus; Vancomycin resistant Staphylococcus aureus |
| Core Tip |
The emergence of increasing vancomycin-resistance in Staphylococcus aureus (SA) isolates, has stirred up the basis of therapeutic approach in staphylococcal infections. Complete vancomycin-resistance is acquired through plasmid transmission of enterococcal gene vanA. However, the development of strains with gradual loss of vancomycin-susceptibility seems to be related to conformational bacterial changes and affects its pathogenicity and even its susceptibility to other antimicrobials (other than vancomycin). It has been observed that the impact of diminished vancomycin susceptibility could not only affect methi-cillin-resistant SA but has also been related to worse prognosis in methicillin-sensitive SA infections. There is yet much to explore to better define the impact of higher vancomycin minimum inhibitory concentration in staphylococcal infections.
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| Publish Date |
2015-05-19 17:49 |
| Citation |
Morales-Cartagena A, Lalueza A, López-Medrano F, Juan RS, Aguado JM. Treatment of methicillin-resistant Staphylococcus aureus infections: Importance of high vancomycin minumum inhibitory concentrations. World J Clin Infect Dis 2015; 5(2): 14-29 |
| URL |
http://www.wjgnet.com/2220-3176/full/v5/i2/14.htm |
| DOI |
http://dx.doi.org/10.5495/wjcid.v5.i2.14 |
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