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10/19/2026 7:27:59 AM | Browse: 0 | Download: 0
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 123604
Country China
Received
2026-05-29 07:40
Peer-Review Started
2026-05-29 07:40
First Decision by Editorial Office Director
Return for Revision
2026-06-16 10:04
Revised
2026-06-27 11:53
Publication Fee Transferred
2026-07-03 12:43
Second Decision by Editor
2026-07-16 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-07-16 03:46
Articles in Press
2026-07-16 03:46
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-09-15 01:07
Publish the Manuscript Online
2026-10-19 07:27
ISSN 1948-9366 (online)
Open Access Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Isolated congenital asplenia with cryptogenic liver fibrosis and a novel SON variant: A case report
Manuscript Source Unsolicited Manuscript
All Author List Yan-Yan Zhang, Yu-Chong Zhao, Li-Ping Chen and Hui-Ling Yu
ORCID
Author(s) ORCID Number
Yu-Chong Zhao http://orcid.org/0000-0003-2245-8541
Li-Ping Chen http://orcid.org/0000-0002-5801-7791
Hui-Ling Yu http://orcid.org/0009-0001-4742-0016
Funding Agency and Grant Number
Funding Agency Grant Number
Hubei Association of Pathophysiology Research Fund 2025HBAP026
Inflammatory Bowel Disease Young Physician Research Fund
Corresponding Author Hui-Ling Yu, PhD, Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Hankou, Wuhan 430030, Hubei, China. y654au@126.com
Key Words Isolated congenital asplenia; Liver cirrhosis; SON gene variant; Whole-exome sequencing; Immune regulation; Case report
Core Tip This case report describes a 33-year-old man with isolated congenital asplenia (ICA) who carries a novel heterozygous SON gene variant, providing a hypothesis-generating clue regarding the genetic basis of ICA. This case highlights the critical challenge of interpreting novel genetic findings in rare congenital anomalies and underscores the need for further studies to elucidate the potential biological significance of SON variants in human disease.
Publish Date 2026-10-19 07:27
Citation

Zhang YY, Zhao YC, Chen LP, Yu HL. Isolated congenital asplenia with cryptogenic liver fibrosis and a novel SON variant: A case report. World J Gastrointest Surg 2026; 18(10): 123604

URL https://www.wjgnet.com/1948-9366/full/v18/i10/123604.htm
DOI https://doi.org/10.4240/wjgs.123604
Full Article (PDF) WJGS-18-123604-with-cover.pdf
CARE Checklist–2016 123604-CARE-Checklist-2016.pdf
Manuscript File 123604_Auto_Edited_015923.docx
Answering Reviewers 123604-answering-reviewers.pdf
Audio Core Tip 123604-audio.mp3
Conflict-of-Interest Disclosure Form 123604-conflict-of-interest-statement.pdf
Copyright License Agreement 123604-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 123604-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 123604-non-native-speakers.pdf
Peer-review Report 123604-peer-reviews.pdf
Scientific Misconduct Check 123604-scientific-misconduct-check.png
CrossCheck Report 123604-crosscheck-report.pdf