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10/9/2026 8:15:10 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 123676
Country China
Received
2026-05-26 06:05
Peer-Review Started
2026-05-26 06:05
First Decision by Editorial Office Director
2026-06-05 03:39
Return for Revision
2026-06-05 03:39
Revised
2026-06-15 12:36
Publication Fee Transferred
2026-06-26 03:51
Second Decision by Editor
2026-06-30 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-30 05:18
Articles in Press
2026-06-30 05:18
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-09-08 08:13
Publish the Manuscript Online
2026-10-09 08:15
ISSN 1948-5204 (online)
Open Access Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pathology
Manuscript Type Case Report
Article Title Primary colonic malignant peripheral nerve sheath tumor with biphasic morphology: A case report
Manuscript Source Unsolicited Manuscript
All Author List Jia-Yue Hu, Jin-Xu He, Xin-Jian Guo and Xiao-Ying Zheng
ORCID
Author(s) ORCID Number
Jia-Yue Hu http://orcid.org/0009-0000-7801-2309
Jin-Xu He http://orcid.org/0009-0009-3460-7111
Xin-Jian Guo http://orcid.org/0000-0003-2517-5096
Xiao-Ying Zheng http://orcid.org/0009-0005-4285-1422
Funding Agency and Grant Number
Funding Agency Grant Number
Qinghai Provincial Science and Technology Department's Innovation Platform Development Support Initiative 2024-SF-L01
Corresponding Author Xiao-Ying Zheng, MD, PhD, Department of Pathology, The Affiliated Hospital of Qinghai University, No. 29 Tongren Road, Xining 810001, Qinghai Province, China. zxy114289181@qq.com
Key Words Malignant peripheral nerve sheath tumor; Colon; H3K27me3; Biphasic morphology; Case report
Core Tip Primary malignant peripheral nerve sheath tumor of the colon is exceptionally rare. We report a sporadic colonic case with unusual biphasic spindle and small round cell morphology, complete loss of H3K27me3, and an extremely aggressive postoperative course despite R0 resection. This case highlights the diagnostic difficulty of high-grade mesenchymal malignancies of the colon and underscores the importance of integrating morphology, immunohistochemistry, and H3K27me3 status for accurate diagnosis, as well as the need for close postoperative surveillance.
Publish Date 2026-10-09 08:15
Citation

Hu JY, He JX, Guo XJ, Zheng XY. Primary colonic malignant peripheral nerve sheath tumor with biphasic morphology: A case report. World J Gastrointest Oncol 2026; 18(10): 123676

URL https://www.wjgnet.com/1948-5204/full/v18/i10/123676.htm
DOI https://doi.org/10.4251/wjgo.123676
Full Article (PDF) WJGO-18-123676-with-cover.pdf
CARE Checklist–2016 123676-CARE-Checklist-2016.pdf
Manuscript File 123676_Auto_Edited_010455.docx
Answering Reviewers 123676-answering-reviewers.pdf
Audio Core Tip 123676-audio.mp3
Conflict-of-Interest Disclosure Form 123676-conflict-of-interest-statement.pdf
Copyright License Agreement 123676-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 123676-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 123676-non-native-speakers.pdf
Supplementary Material 123676-supplementary-material.pdf
Peer-review Report 123676-peer-reviews.pdf
Scientific Misconduct Check 123676-scientific-misconduct-check.png
CrossCheck Report 123676-crosscheck-report.pdf