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Publication Name World Journal of Hepatology
Manuscript ID 123924
Country China
Received
2026-06-02 07:36
Peer-Review Started
2026-06-02 07:37
First Decision by Editorial Office Director
Return for Revision
2026-07-07 03:15
Revised
2026-07-17 07:36
Publication Fee Transferred
Second Decision by Editor
2026-08-28 02:55
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-08-28 09:25
Articles in Press
2026-08-28 09:25
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-09-07 03:08
Publish the Manuscript Online
2026-09-17 05:48
ISSN 1948-5182 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Radiologic partial response poorly predicts pathologic complete response in hepatocellular carcinoma after conversion therapy
Manuscript Source Invited Manuscript
All Author List Chi Xu, Qiong-Yu Liang, Jia-Peng Sun, Kang Zhou, Jie Pan and Hai-Tao Zhao
ORCID
Author(s) ORCID Number
Jie Pan http://orcid.org/0009-0001-5893-2690
Hai-Tao Zhao http://orcid.org/0000-0002-3444-8044
Funding Agency and Grant Number
Corresponding Author Jie Pan, MD, PhD, Department of Radiology, Peking Union Medical College Hospital, No. 1 Shuaifuyuan Wangfujing, Dongcheng District, Beijing 100730, China. markpan6885@163.com
Key Words Hepatocellular carcinoma; Conversion therapy; Pathologic complete response; Radiologic-pathologic correlation; Surgical resection
Core Tip Radiologic response is widely used to assess treatment efficacy in hepatocellular carcinoma after conversion therapy, yet its correlation with pathological response remains uncertain. In this study, radiologic partial response assessed by both Response Evaluation Criteria in Solid Tumours (RECIST) version 1.1 and modified RECIST showed poor concordance with pathologic complete response (pCR). Although all patients achieving pCR were classified as responders by modified RECIST, most radiologic responders still had residual viable tumor. These findings underscore the limitations of imaging-based response assessment and support the integration of additional biomarkers to improve preoperative evaluation and treatment planning.
Publish Date 2026-09-17 05:48
Citation

Xu C, Liang QY, Sun JP, Zhou K, Pan J, Zhao HT. Radiologic partial response poorly predicts pathologic complete response in hepatocellular carcinoma after conversion therapy. World J Hepatol 2026; 18(9): 123924

URL https://www.wjgnet.com/1948-5182/full/v18/i9/123924.htm
DOI https://doi.org/10.4254/wjh.123924
Full Article (PDF) WJH-18-123924-with-cover.pdf
STROBE Statement 123924-STROBE-statement.pdf
Manuscript File 123924_Auto_Edited_081943.docx
Answering Reviewers 123924-answering-reviewers.pdf
Audio Core Tip 123924-audio.mp3
Biostatistics Review Certificate 123924-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 123924-conflict-of-interest-statement.pdf
Copyright License Agreement 123924-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 123924-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 123924-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 123924-non-native-speakers.pdf
Peer-review Report 123924-peer-reviews.pdf
Scientific Misconduct Check 123924-scientific-misconduct-check.png
CrossCheck Report 123924-crosscheck-report.pdf