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Articles Published Processes
11/11/2026 5:49:21 AM | Browse: 1 | Download: 0
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Received |
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2026-06-05 06:40 |
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Peer-Review Started |
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2026-06-05 06:41 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-07-27 07:29 |
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Revised |
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2026-08-10 04:05 |
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Publication Fee Transferred |
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2026-09-01 14:01 |
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Second Decision by Editor |
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2026-09-24 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-09-24 08:48 |
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Articles in Press |
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2026-09-24 08:48 |
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Edit the Manuscript by Language Editor |
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2026-09-30 02:03 |
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Typeset the Manuscript |
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2026-10-19 06:37 |
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Publish the Manuscript Online |
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2026-11-11 05:49 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Review |
| Article Title |
Clinical advances in later-line therapy for metastatic or refractory colorectal cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Li Ma, Xia Liu, Ying Zhang and Yong Luo |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Yong Luo, Cancer Center, West China Hospital, No. 37 Guo Xue Alley, Chengdu 610065, Sichuan Province, China. luoyong@wchscu.edu.cn |
| Key Words |
Metastatic colorectal cancer; Treatment-refractory; Targeted therapy; Immunotherapy; Treatment strategy |
| Core Tip |
This narrative review synthesizes the latest publications from PubMed and other databases published in the past five years. It mainly analyzes trial design, enrolled populations and primary endpoints. By reviewing outcomes of combination regimens and phase I/II trials of novel agents, we evaluate the clinical practicability of various later-line therapies for colorectal cancer. Our team emphasizes combination strategies of existing drugs, arguing improved efficacy does not solely rely on new drug development. |
| Publish Date |
2026-11-11 05:49 |
| Citation |
Ma L, Liu X, Zhang Y, Luo Y. Clinical advances in later-line therapy for metastatic or refractory colorectal cancer. World J Gastroenterol 2027; 33(2): 123996
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| URL |
https://www.wjgnet.com/1007-9327/full/v33/i2/123996.htm |
| DOI |
https://doi.org/10.3748/wjg.123996 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
