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10/29/2026 7:19:22 AM | Browse: 2 | Download: 0
Publication Name World Journal of Psychiatry
Manuscript ID 124037
Country China
Received
2026-06-04 03:07
Peer-Review Started
2026-06-04 03:07
First Decision by Editorial Office Director
Return for Revision
2026-07-06 08:06
Revised
2026-07-13 12:30
Publication Fee Transferred
2026-08-03 13:23
Second Decision by Editor
2026-08-28 02:55
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-08-28 09:27
Articles in Press
2026-08-28 09:27
Edit the Manuscript by Language Editor
2026-09-08 17:28
Typeset the Manuscript
2026-10-09 02:45
Publish the Manuscript Online
2026-10-29 07:19
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Observational Study
Article Title Association between systemic immune-inflammation index and symptoms of depression and anxiety in type 2 diabetes mellitus patients
Manuscript Source Unsolicited Manuscript
All Author List Xiao-Yu Pan, Yi-Kun Wang, Ya-Qin Ding, Nuo-Jin Wang, Tian-Rong Pan and Xing Zhong
ORCID
Author(s) ORCID Number
Tian-Rong Pan http://orcid.org/0000-0002-4293-4579
Xing Zhong http://orcid.org/0000-0002-3485-1036
Funding Agency and Grant Number
Funding Agency Grant Number
Health Research Program of Anhui AHWJ2023BAc10010
Clinical and Translational Research Project of Anhui Province 202427b10020055
National Natural Science Foundation of China 32571507
Corresponding Author Xing Zhong, Professor, Department of Endocrinology, The Second Affiliated Hospital of Anhui Medical University, No. 678 Furong Road, Economic and Technological Development Zone, Hefei 230601, Anhui Province, China. zhongxing@ahmu.edu.cn
Key Words Anxiety; Depression; Systemic immune-inflammatory index; Type 2 diabetes mellitus; 9-item Patient Health Questionnaire; 7-item Generalized Anxiety Disorder
Core Tip Chronic inflammation is implicated in the psychological comorbidities of type 2 diabetes mellitus (T2DM). This cross-sectional study enrolling 402 hospitalized T2DM patients reveals that elevated systemic immune-inflammation index is independently associated with higher prevalence of elevated depressive symptoms, anxiety symptoms and their comorbidity, presenting a significant non-linear dose-response pattern. Systemic immune-inflammatory index may act as an auxiliary inflammatory biomarker for psychological symptom stratification in hospitalized T2DM patients.
Publish Date 2026-10-29 07:19
Citation

Pan XY, Wang YK, Ding YQ, Wang NJ, Pan TR, Zhong X. Association between systemic immune-inflammation index and symptoms of depression and anxiety in type 2 diabetes mellitus patients. World J Psychiatry 2026; 16(11): 124037

URL https://www.wjgnet.com/2220-3206/full/v16/i11/124037.htm
DOI https://doi.org/10.5498/wjp.124037
Full Article (PDF) WJP-16-124037-with-cover.pdf
STROBE Statement 124037-STROBE-statement.pdf
Manuscript File 124037_Auto_Edited_011650.docx
Answering Reviewers 124037-answering-reviewers.pdf
Audio Core Tip 124037-audio.mp3
Biostatistics Review Certificate 124037-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 124037-conflict-of-interest-statement.pdf
Copyright License Agreement 124037-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 124037-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 124037-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 124037-non-native-speakers.pdf
Supplementary Material 124037-supplementary-material.pdf
Peer-review Report 124037-peer-reviews.pdf
Scientific Misconduct Check 124037-scientific-misconduct-check.png
CrossCheck Report 124037-crosscheck-report.pdf