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Articles Published Processes
11/5/2026 2:51:01 AM | Browse: 3 | Download: 1
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Received |
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2026-06-04 03:07 |
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Peer-Review Started |
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2026-06-04 03:07 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-07-15 02:30 |
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Revised |
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2026-07-16 10:41 |
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Publication Fee Transferred |
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2026-07-24 06:34 |
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Second Decision by Editor |
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2026-07-30 02:32 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-07-30 10:45 |
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Articles in Press |
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2026-07-30 10:45 |
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Edit the Manuscript by Language Editor |
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2026-07-31 03:43 |
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Typeset the Manuscript |
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2026-10-19 00:30 |
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Publish the Manuscript Online |
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2026-11-05 02:51 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Elevated pretreatment neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio predict poor survival in cholangiocarcinoma: A large-scale meta-analysis of 48 cohorts
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Wen-Miao Cai, Wei Jiang, Bao-Feng He, Jun-Jie Yu, Xian-Hua Zeng, Lei Peng and Sun Liu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Lei Peng, Department of Orthopedics, The Third Affiliated Hospital of Southern Medical University, Zhongshan Avenue, Guangzhou 510000, Guangdong Province, China. 1015425249@qq.com |
| Key Words |
Cholangiocarcinoma; Neutrophil-to-lymphocyte ratio; Platelet-to-lymphocyte ratio; Prognosis; Meta-analysis |
| Core Tip |
Pretreatment neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio serve as significant prognostic biomarkers for cholangiocarcinoma. This meta-analysis of 48 cohorts confirms that elevated NLR and platelet-to-lymphocyte ratio correlate with poorer overall and disease-free survival. Notably, NLR demonstrates superior predictive value in patients receiving palliative therapy compared to those undergoing curative surgery. These findings suggest NLR is a valuable tool for risk stratification in unresectable cases. However, the lack of standardized cut-off values necessitates cautious clinical application and further prospective validation before routine implementation. |
| Publish Date |
2026-11-05 02:51 |
| Citation |
Cai WM, Jiang W, He BF, Yu JJ, Zeng XH, Peng L, Liu S. Elevated pretreatment neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio predict poor survival in cholangiocarcinoma: A large-scale meta-analysis of 48 cohorts. World J Gastrointest Oncol 2026; 18(11): 124040
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| URL |
https://www.wjgnet.com/1948-5204/full/v18/i11/124040.htm |
| DOI |
https://doi.org/10.4251/wjgo.124040 |
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