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9/9/2026 9:45:19 AM | Browse: 4 | Download: 0
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 124094
Country China
Received
2026-06-05 11:36
Peer-Review Started
2026-06-05 11:37
First Decision by Editorial Office Director
Return for Revision
2026-06-22 02:14
Revised
2026-06-30 08:58
Publication Fee Transferred
2026-07-08 02:09
Second Decision by Editor
2026-08-28 02:55
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-08-28 09:28
Articles in Press
2026-08-28 09:28
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-09-04 03:10
Publish the Manuscript Online
2026-09-09 09:45
ISSN 1948-5204 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, lymphocyte-to-monocyte ratio and systemic immune-inflammation index predict survival in HER2-negative advanced gastric cancer
Manuscript Source Unsolicited Manuscript
All Author List Xin Zheng, Jing Chen and Meng-Ting Li
ORCID
Author(s) ORCID Number
Xin Zheng http://orcid.org/0009-0008-4070-261X
Funding Agency and Grant Number
Corresponding Author Xin Zheng, Chief Physician, Clinical Laboratory, Laboratory Department, Chuzhou Hospital Affiliated to Anhui Medical University (Chuzhou First People's Hospital), Chuzhou 239000, Anhui China, Department of Laboratory Medicine, Chuzhou Hospital Affiliated to Anhui Medical University (Chuzhou First People’s Hospital), 369 Zuiweng West Road, Nanqiao District, Chuzhou City, Anhui Province, Chuzhou 239000, Anhui Province, China. sunnyacmilan@163.com
Key Words Inflammatory markers; HER2-negative; Advanced gastric cancer; Survival outcomes; Predictive value
Core Tip This retrospective cohort study of 262 patients with human epidermal growth factor receptor 2-negative advanced gastric cancer demonstrates that pretreatment peripheral blood neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), and systemic immune-inflammation index (SII) are independent predictors of overall survival. Elevated NLR, PLR, and SII were risk factors, while elevated LMR was protective. The combined four marker nomogram achieved an area under the curve of 0.764, offering a simple, cost-effective tool for early risk stratification and treatment optimization in this population.
Publish Date 2026-09-09 09:45
Citation

Zheng X, Chen J, Li MT. Neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, lymphocyte-to-monocyte ratio and systemic immune-inflammation index predict survival in HER2-negative advanced gastric cancer. World J Gastrointest Oncol 2026; 18(9): 124094

URL https://www.wjgnet.com/1948-5204/full/v18/i9/124094.htm
DOI https://doi.org/10.4251/wjgo.124094
Full Article (PDF) WJGO-18-124094-with-cover.pdf
STROBE Statement 124094-STROBE-statement.pdf
Manuscript File 124094_Auto_Edited_031712.docx
Answering Reviewers 124094-answering-reviewers.pdf
Audio Core Tip 124094-audio.mp3
Biostatistics Review Certificate 124094-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 124094-conflict-of-interest-statement.pdf
Copyright License Agreement 124094-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 124094-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 124094-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 124094-non-native-speakers.pdf
Peer-review Report 124094-peer-reviews.pdf
Scientific Misconduct Check 124094-scientific-misconduct-check.png
CrossCheck Report 124094-crosscheck-report.pdf