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8/18/2026 3:51:53 AM | Browse: 1 | Download: 0
Publication Name World Journal of Hepatology
Manuscript ID 124108
Country Israel
Received
2026-06-08 02:00
Peer-Review Started
2026-06-08 02:01
First Decision by Editorial Office Director
Return for Revision
2026-06-25 16:45
Revised
2026-06-30 16:51
Publication Fee Transferred
2026-07-28 03:07
Second Decision by Editor
2026-07-31 02:50
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-07-31 10:43
Articles in Press
2026-07-31 10:43
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-08-06 08:06
Publish the Manuscript Online
2026-08-18 03:51
ISSN 1948-5182 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Acute hepatitis B in the vaccination era: Predictors of functional cure and chronicity
Manuscript Source Unsolicited Manuscript
All Author List David Yardeni, Julianna Gershbaum Tobin, Bryan Itkowitz, Inna Lipnizkiy, Ali Abu Juma’a, Naim Abu-Freha, Ayelet Keren-Naus, May Turgeman, Anat Nevo-Shor, Robert Gareth Gish and Ohad Etzion
ORCID
Author(s) ORCID Number
David Yardeni http://orcid.org/0000-0002-4078-7173
Ohad Etzion http://orcid.org/0000-0001-9254-2154
Funding Agency and Grant Number
Corresponding Author David Yardeni, MD, Department of Gastroenterology and Liver Diseases, Soroka University Medical Center, 151 Rager Blvd., Beersheba 84101, Southern, Israel. yardeda@post.bgu.ac.il
Key Words Hepatitis B; Diabetes mellitus; Socioeconomic status; Vaccination; Nucleos(t)ide analogues
Core Tip The widespread availability of the universal hepatitis B virus (HBV) vaccination reduced acute HBV incidence in developed countries. Acute HBV usually resolves with functional cure in > 95% of adults. In our study we evaluated all acute HBV cases in southern Israel between 2004-2022 and found a striking 34% chronicity rate. Further analysis revealed that a background of diabetes and low socioeconomic status were found to strongly predict chronic infection. These findings highlight the need for risk stratification in acute HBV patients from vulnerable populations.
Publish Date 2026-08-18 03:51
Citation

Yardeni D, Gershbaum Tobin J, Itkowitz B, Lipnizkiy I, Abu Juma’a A, Abu-Freha N, Keren-Naus A, Turgeman M, Nevo-Shor A, Gish RG, Etzion O. Acute hepatitis B in the vaccination era: Predictors of functional cure and chronicity. World J Hepatol 2026; 18(8): 124108

URL https://www.wjgnet.com/1948-5182/full/v18/i8/124108.htm
DOI https://doi.org/10.4254/wjh.124108
Full Article (PDF) WJH-18-124108-with-cover.pdf
Manuscript File 124108_Auto_Edited_004559.docx
Answering Reviewers 124108-answering-reviewers.pdf
Audio Core Tip 124108-audio.m4a
Biostatistics Review Certificate 124108-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 124108-conflict-of-interest-statement.pdf
Copyright License Agreement 124108-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 124108-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 124108-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 124108-non-native-speakers.pdf
Supplementary Material 124108-supplementary-material.pdf
Peer-review Report 124108-peer-reviews.pdf
Scientific Misconduct Check 124108-scientific-misconduct-check.png
Scientific Editor Work List 124108-scientific-editor-work-list.pdf
CrossCheck Report 124108-crosscheck-report.pdf