Publication Name	World Journal of Gastroenterology
Manuscript ID	12415
Country	Japan

Received	2014-07-07 17:25
Peer-Review Started	2014-07-08 15:16
To Make the First Decision	2014-08-06 17:20
Return for Revision	2014-08-12 17:31
Revised	2014-09-01 12:58
Second Decision	2014-10-15 07:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-10-15 08:12
Articles in Press	2014-10-15 08:26
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-11-14 03:22
Typeset the Manuscript	2015-02-02 14:29
Publish the Manuscript Online	2015-02-11 16:38

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Predictors of kidney tubular dysfunction induced by adefovir treatment for chronic hepatitis B
Manuscript Source	Unsolicited Manuscript
All Author List	Motohiro Shimizu, Norihiro Furusyo, Hiroaki Ikezaki, Eiichi Ogawa, Takeo Hayashi, Takeshi Ihara, Yuji Harada, Kazuhiro Toyoda, Masayuki Murata and Jun Hayashi
Funding Agency and Grant Number	Funding Agency Grant Number Comprehensive Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan(In part)
Corresponding Author	Norihiro Furusyo, MD, PhD, Department of General Internal Medicine, Kyushu University Hospital, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. furusyo@gim.med.kyushu-u.ac.jp
Key Words	Adefovir dipivoxil; Proximal kidney tubular dysfunction; Fanconi syndrome; Hepatitis B virus
Core Tip	This paper reports that high prevalence rates of proximal kidney tubular dysfunction (30.0%) and symptomatic osteomalacia (10.0%) were found for chronic hepatitis B virus infection patients treated with low-dose adefovir dipivoxil (ADV) and that age at the initiation of ADV and treatment duration of ADV were independently associated with the development of proximal kidney tubular dysfunction.
Publish Date	2015-02-11 16:38
Citation	Shimizu M, Furusyo N, Ikezaki H, Ogawa E, Hayashi T, Ihara T, Harada Y, Toyoda K, Murata M, Hayashi J. Predictors of kidney tubular dysfunction induced by adefovir treatment for chronic hepatitis B. World J Gastroenterol 2015; 21(7): 2116-2123
URL	http://www.wjgnet.com/1007-9327/full/v21/i7/2116.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i7.2116

Full Article (PDF)	WJG-21-2116.pdf
Full Article (Word)	WJG-21-2116.doc
Manuscript File	12415-Review.docx
Answering Reviewers	12415-Answering reviewers.pdf
Copyright License Agreement	12415-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	12415-Language certificate.pdf
Peer-review Report	12415-Peer review(s).pdf
Scientific Misconduct Check	12415-CrossCheck.jpg
Scientific Editor Work List	12415-Scientific editor work list.pdf