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Articles Published Processes
9/24/2026 6:23:42 AM | Browse: 0 | Download: 0
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Received |
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2026-06-09 03:21 |
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Peer-Review Started |
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2026-06-09 03:21 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-07-08 06:32 |
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Revised |
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2026-07-13 07:41 |
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Publication Fee Transferred |
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2026-07-27 07:07 |
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Second Decision by Editor |
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2026-08-13 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-08-26 08:45 |
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Articles in Press |
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2026-08-26 08:45 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-09-17 00:21 |
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Publish the Manuscript Online |
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2026-09-24 06:23 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Neurosciences |
| Manuscript Type |
Minireviews |
| Article Title |
Induced pluripotent stem cell-derived neuronal models in psychiatry: Mechanistic insights and translational horizons
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Moria Maman, Orit Goldman, Talia Cohen Solal and Daphna Laifenfeld |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Moria Maman, PhD, Research and Development, NeuroKaire, Yigal Alon 126, Tel Aviv-Yafo 6744332, Tel Aviv, Israel. moria@neurokaire.com |
| Key Words |
Induced pluripotent stem cells; Schizophrenia; Bipolar disorder; Major depressive disorder; Autism spectrum disorder; Attention-deficit hyperactivity disorder; Precision psychiatry; In vitro disease modeling |
| Core Tip |
Human induced pluripotent stem cell-derived neuronal models are transforming psychiatric research by enabling direct investigation of patient-specific neural phenotypes in a human genetic context. Beyond disease modeling, emerging evidence suggests that quantitative functional phenotyping can identify biologically meaningful patient subgroups and treatment-response signatures. This review synthesizes findings across major psychiatric disorders and proposes a conceptual shift from reproducing diagnostic categories in vitro toward mechanism-based stratification. Such approaches may bridge the gap between psychiatric genetics and clinical decision-making, advancing the development of precision psychiatry. |
| Publish Date |
2026-09-24 06:23 |
| Citation |
Maman M, Goldman O, Cohen Solal T, Laifenfeld D. Induced pluripotent stem cell-derived neuronal models in psychiatry: Mechanistic insights and translational horizons. World J Stem Cells 2026; 18(9): 124169
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| URL |
https://www.wjgnet.com/1948-0210/full/v18/i9/124169.htm |
| DOI |
https://doi.org/10.4252/wjsc.124169 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
