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Articles Published Processes
10/26/2026 6:39:37 AM | Browse: 0 | Download: 0
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Received |
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2026-06-10 08:36 |
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Peer-Review Started |
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2026-06-10 08:36 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-07-08 06:48 |
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Revised |
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2026-07-20 15:53 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-08-14 02:39 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-08-14 09:43 |
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Articles in Press |
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2026-08-14 09:43 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-09-28 09:36 |
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Publish the Manuscript Online |
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2026-10-26 06:39 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Editorial |
| Article Title |
Mediator complex subunit 18: A novel breast cancer stem cell marker in tumor microenvironment
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ying-Zhu Zhang, Yue-Feng Zhang and Yi-Gang Wang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Joint Fund of Zhejiang Provincial Natural Science Foundation of China Under Grant |
LKLY25H160002 |
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| Corresponding Author |
Yue-Feng Zhang, MD, Department of Hematology, First People’s Hospital of Linping District, No. 369 Yingbin Road, Nanyuan Street, Hangzhou 311100, Zhejiang Province, China. zhangyuefeng@zju.edu.cn |
| Key Words |
Breast cancer; Breast cancer stem cell; Mediator complex subunit 18; Tumor microenvironment; Multi-omics analysis |
| Core Tip |
Breast cancer exhibits a tendency toward drug resistance and recurrence due to the presence of breast cancer stem cells (BCSCs). Therefore, the screening and validation of breast cancer biomarkers are crucial for diagnosis, treatment, and prognosis. Mediator complex subunit 18 (MED18) has emerged as a novel BCSC biomarker, positioned at the intersection of BCSC regulation and tumor microenvironment interactions. Although its identification demonstrates promising diagnostic and therapeutic potential, further mechanism validation through in vitro and in vivo studies is required to translate MED18 from a biomarker into a clinically actionable target. |
| Publish Date |
2026-10-26 06:39 |
| Citation |
Zhang YZ, Zhang YF, Wang YG. Mediator complex subunit 18: A novel breast cancer stem cell marker in tumor microenvironment. World J Stem Cells 2026; 18(10): 124204
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| URL |
https://www.wjgnet.com/1948-0210/full/v18/i10/124204.htm |
| DOI |
https://doi.org/10.4252/wjsc.124204 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
