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Articles Published Processes
8/18/2026 3:51:55 AM | Browse: 0 | Download: 0
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Received |
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2026-06-09 01:29 |
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Peer-Review Started |
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2026-06-09 01:30 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-06-16 06:53 |
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Revised |
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2026-07-09 21:11 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-07-23 07:39 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-07-27 09:06 |
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Articles in Press |
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2026-07-27 09:06 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-08-11 00:44 |
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Publish the Manuscript Online |
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2026-08-18 03:51 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Metabolic dysfunction-associated steatotic liver disease and the consequence of extra-hepatic malignancy
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Benjamin Blaske, Michael Ward and Ragesh Babu Thandassery |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ragesh Babu Thandassery, Department of Internal Medicine, Division of Gastronterology, University of Arkansas For Medical Sciences, 4300 W 7th St, Little Rock, AR 72205, United States. doc.ragesh@gmail.com |
| Key Words |
Metabolic dysfunction-associated steatotic liver disease; Extra-hepatic malignancy; Colorectal cancer; Pancreatic cancer; Breast cancer; Insulin resistance; Obesity; Cancer surveillance; Gut microbiome; Inflammation |
| Core Tip |
Metabolic dysfunction-associated steatotic liver disease (MASLD) confers increased risk of extra-hepatic malignancies spanning multiple organ systems, beyond its well-recognized association with hepatocellular carcinoma. Shared oncogenic pathways which include insulin resistance, chronic systemic inflammation, lipotoxicity, and gut dysbiosis, link MASLD to both gastrointestinal (GI) cancers (colorectal, pancreatic, esophagogastric, biliary) and non-GI cancers (breast, gynecologic, thyroid, urinary, lung). Globally, the burden and prevalence of MASLD is rising, with young-onset disease and advanced fibrosis as key risk amplifiers. Dedicated cancer surveillance protocols for MASLD populations are urgently needed. |
| Publish Date |
2026-08-18 03:51 |
| Citation |
Blaske B, Ward M, Thandassery RB. Metabolic dysfunction-associated steatotic liver disease and the consequence of extra-hepatic malignancy. World J Hepatol 2026; 18(8): 124224
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| URL |
https://www.wjgnet.com/1948-5182/full/v18/i8/124224.htm |
| DOI |
https://doi.org/10.4254/wjh.124224 |
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