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9/23/2026 8:57:28 AM | Browse: 3 | Download: 13
Publication Name World Journal of Clinical Oncology
Manuscript ID 124416
Country China
Received
2026-06-15 08:34
Peer-Review Started
2026-06-15 08:34
First Decision by Editorial Office Director
Return for Revision
2026-07-24 06:38
Revised
2026-08-05 23:57
Publication Fee Transferred
2026-09-01 09:14
Second Decision by Editor
2026-09-22 03:46
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-09-22 09:54
Articles in Press
2026-09-22 09:54
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-09-23 02:21
Publish the Manuscript Online
2026-09-23 08:57
ISSN 2218-4333 (online)
Open Access Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Observational Study
Article Title Efficacy of two programmed cell death 1 combination regimens in recurrent and/or metastatic head and neck carcinoma: A real-world retrospective study
Manuscript Source Unsolicited Manuscript
All Author List Jia-Xin Wang, Tian-Xiao Wang, Yun-Tao Song, Guo-Hui Xu, Ya-Bing Zhang and Bin Zhang
ORCID
Author(s) ORCID Number
Jia-Xin Wang http://orcid.org/0009-0002-6318-6108
Bin Zhang http://orcid.org/0000-0002-1624-2181
Funding Agency and Grant Number
Corresponding Author Bin Zhang, Department of Head and Neck Surgery, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, No. 52 Fucheng Road, Haidian District, Beijing 100142, China. docbinzhang@hotmail.com
Key Words Head and neck squamous cell carcinoma; Programmed cell death 1 inhibitor; Cetuximab; Anlotinib; Immuno-targeted therapy
Core Tip Programmed cell death 1 (PD-1) inhibitors combined with cetuximab or anlotinib exhibit distinct therapeutic profiles in recurrent and/or metastatic head and neck squamous cell carcinoma. In this real-world cohort study, PD-1 inhibitor plus cetuximab was associated with significantly prolonged overall survival, whereas PD-1 inhibitor plus anlotinib showed favorable tumor response and disease control. These distinct efficacy profiles may help inform individualized treatment selection for PD-1-based immunotherapy-targeted therapy combinations.
Publish Date 2026-09-23 08:57
Citation

Wang JX, Wang TX, Song YT, Xu GH, Zhang YB, Zhang B. Efficacy of two programmed cell death 1 combination regimens in recurrent and/or metastatic head and neck carcinoma: A real-world retrospective study. World J Clin Oncol 2026; 17(9): 124416

URL https://www.wjgnet.com/2218-4333/full/v17/i9/124416.htm
DOI https://doi.org/10.5306/wjco.124416
Full Article (PDF) WJCO-17-124416-with-cover.pdf
STROBE Statement 124416-STROBE-statement.pdf
Manuscript File 124416_Auto_Edited_024441.docx
Answering Reviewers 124416-answering-reviewers.pdf
Audio Core Tip 124416-audio.mp3
Biostatistics Review Certificate 124416-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 124416-conflict-of-interest-statement.pdf
Copyright License Agreement 124416-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 124416-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 124416-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 124416-non-native-speakers.pdf
Supplementary Material 124416-supplementary-material.pdf
Peer-review Report 124416-peer-reviews.pdf
Scientific Misconduct Check 124416-scientific-misconduct-check.png
CrossCheck Report 124416-crosscheck-report.pdf