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Articles Published Processes
11/11/2026 5:49:20 AM | Browse: 0 | Download: 0
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Received |
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2026-06-16 03:23 |
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Peer-Review Started |
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2026-06-16 03:24 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-08-11 09:16 |
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Revised |
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2026-08-24 12:01 |
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Publication Fee Transferred |
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2026-10-01 04:50 |
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Second Decision by Editor |
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2026-10-23 02:59 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-10-23 09:07 |
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Articles in Press |
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2026-10-23 09:07 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-10-27 05:54 |
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Publish the Manuscript Online |
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2026-11-11 05:49 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Randomized Controlled Trial |
| Article Title |
Fexuprazan vs esomeprazole for endoscopic submucosal dissection-induced gastric ulcer healing: A double-blind randomized controlled trial
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hye Kyung Hyun, Jin Ho Hwang, Nak-Hoon Son, So Hyeon Gwon, Da Hyun Jung and Cheal Wung Huh |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Cheal Wung Huh, Associate Professor, Department of Internal Medicine, Yongin Severance Hospital, Yonsei University College of Medicine, Dongbaekjukjeon-daero Road, Giheung-gu District, Yongin 16995, Gyeonggi-do, South Korea. huhcw@yuhs.ac |
| Key Words |
Fexuprazan; Potassium-competitive acid blocker; Esomeprazole; Endoscopic submucosal dissection; Gastric ulcer; Randomized controlled trial |
| Core Tip |
This double-blind, double-dummy randomized controlled trial compared the potassium-competitive acid blocker fexuprazan with the proton pump inhibitor esomeprazole for the healing of artificial gastric ulcers after endoscopic submucosal dissection. Ulcer healing was assessed endoscopically at 4 weeks and 8 weeks. Fexuprazan achieved a significantly higher complete healing rate at 8 weeks in the pre-specified PP analysis (90.2% vs 75.0%) and greater ulcer shrinkage at both time points, although the difference was not significant in the modified intention-to-treat population. In an exploratory analysis, the model-estimated healing time was shorter with fexuprazan, particularly for large baseline ulcers (≥ 800 mm2). The safety profile was comparable between groups. |
| Publish Date |
2026-11-11 05:49 |
| Citation |
Hyun HK, Hwang JH, Son NH, Gwon SH, Jung DH, Huh CW. Fexuprazan vs esomeprazole for endoscopic submucosal dissection-induced gastric ulcer healing: A double-blind randomized controlled trial. World J Gastroenterol 2027; 33(2): 124419
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| URL |
https://www.wjgnet.com/1007-9327/full/v33/i2/124419.htm |
| DOI |
https://doi.org/10.3748/wjg.124419 |
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