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10/21/2026 2:09:39 AM | Browse: 1 | Download: 0
Publication Name World Journal of Hepatology
Manuscript ID 124577
Country China
Received
2026-06-23 09:03
Peer-Review Started
2026-06-23 09:04
First Decision by Editorial Office Director
Return for Revision
2026-07-27 08:09
Revised
2026-08-07 14:05
Publication Fee Transferred
Second Decision by Editor
2026-09-21 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-09-21 09:43
Articles in Press
2026-09-21 09:43
Edit the Manuscript by Language Editor
2026-09-26 19:17
Typeset the Manuscript
2026-10-12 00:39
Publish the Manuscript Online
2026-10-21 02:09
ISSN 1948-5182 (online)
Open Access Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, General & Internal
Manuscript Type Retrospective Study
Article Title Risk factors and predictive model for hepatitis B virus deoxyribonucleic acid elevation in mid-to-late pregnancy with low viremia
Manuscript Source Unsolicited Manuscript
All Author List Zi‑Ren Chen, Hui‑Hui Chen, Bing‑Wang Jie, Ting‑Ting Peng, Ying Lin, Ya‑Wen Geng, Yu‑Wei Shen, Yue‑Ying Deng, Dan Xie, Li‑Li Yang and Shi Ouyang
ORCID
Author(s) ORCID Number
Zi‑Ren Chen http://orcid.org/0000-0002-0484-9453
Hui‑Hui Chen http://orcid.org/0009-0006-0110-4591
Ying Lin http://orcid.org/0009-0009-7405-155X
Yue‑Ying Deng http://orcid.org/0009-0002-0615-9015
Li‑Li Yang http://orcid.org/0000-0003-1306-0806
Shi Ouyang http://orcid.org/0000-0003-0173-3276
Funding Agency and Grant Number
Corresponding Author Shi Ouyang, Department of Infectious Diseases, The Fifth Affiliated Hospital of Guangzhou Medical University, No. 621 Gangwan Road, Huangpu District, Guangzhou 510700, Guangdong Province, China. ouyangshi@gzhmu.edu.cn
Key Words Chronic hepatitis B; Pregnancy; Low viral load; Mother-to-child transmission; Risk factors; Predictive model
Core Tip This study identifies maternal age and baseline hepatitis B virus DNA ≥ 100 IU/mL as independent predictors of viral load elevation during pregnancy. We developed and validated a nomogram-based model with good discrimination (area under the curve 0.71) and excellent calibration, offering a practical bedside tool for early risk stratification in routine antenatal care. This approach enables timely intervention and personalized monitoring, potentially reducing mother to child transmission and improving pregnancy outcomes in chronic hepatitis B carriers.
Publish Date 2026-10-21 02:09
Citation

Chen Z, Chen H, Jie B, Peng T, Lin Y, Geng Y, Shen Y, Deng Y, Xie D, Yang L, Ouyang S. Risk factors and predictive model for hepatitis B virus deoxyribonucleic acid elevation in mid-to-late pregnancy with low viremia. World J Hepatol 2026; 18(10): 124577

URL https://www.wjgnet.com/1948-5182/full/v18/i10/124577.htm
DOI https://doi.org/10.4254/wjh.124577
Full Article (PDF) WJH-18-124577-with-cover.pdf
Manuscript File 124577_Auto_Edited_005505.docx
Answering Reviewers 124577-answering-reviewers.pdf
Audio Core Tip 124577-audio.mp3
Biostatistics Review Certificate 124577-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 124577-conflict-of-interest-statement.pdf
Copyright License Agreement 124577-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 124577-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 124577-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 124577-non-native-speakers.pdf
Peer-review Report 124577-peer-reviews.pdf
Scientific Misconduct Check 124577-scientific-misconduct-check.png
CrossCheck Report 124577-crosscheck-report.pdf