Publication Name	World Journal of Pharmacology
Manuscript ID	12462
Country	United States

Received	2014-07-10 08:36
Peer-Review Started	2014-07-10 11:01
To Make the First Decision	2014-09-16 11:09
Return for Revision	2014-09-23 17:30
Revised	2014-10-22 14:27
Second Decision	2014-12-11 17:19
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-12-17 16:23
Articles in Press	2014-12-17 16:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-02-28 11:44
Publish the Manuscript Online	2015-03-12 19:39

ISSN	2220-3192 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Urology & Nephrology
Manuscript Type	Review
Article Title	Updates on therapies for chronic prostatitis/chronic pelvic pain syndrome
Manuscript Source	Invited Manuscript
All Author List	Asfandyar Khan and Adam B Murphy
Funding Agency and Grant Number
Corresponding Author	Asfandyar Khan, MD, Department of Urology, Northwestern University Feinberg School of Medicine, 303 E. Chicago Ave., Tarry 16-729, Chicago, IL 60611, United States. a-khan@northwestern.edu
Key Words	Chronic prostatitis; Antibiotics; Myofascial trigger point; Pelvic biofeedback; Chronic pelvic pain syndrome; Phytotherapy; Nanobacteria; Dysfunctional voiding; Acupuncture
Core Tip	Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is difficult-to-treat because of the multitude of potential etiologies that are not easily observed and delayed diagnosis. Pharmacological monotherapy with antibiotics, alpha-blockers and anti-inflammatories provide significant symptomatic improvement in a limited number of patients. Multidrug therapies are recommended for monotherapy refractory patients. Complementary and interventional therapies such as acupuncture, myofascial trigger point release and pelvic floor biofeedback can provide additional symptomatic relief. Current recommendations involve a treatment algorithm based on UPOINT phenotypic presentation for CP/CPPS patients. Keeping in mind the high prevalence of CP/CPPS, development of novel therapies and an effective vaccine for prevention of CP/CPPS is crucial.
Publish Date	2015-03-12 19:39
Citation	Khan A, Murphy AB. Updates on therapies for chronic prostatitis/chronic pelvic pain syndrome. World J Pharmacol 2015; 4(1): 1-16
URL	http://www.wjgnet.com/2220-3192/full/v4/i1/1.htm
DOI	http://dx.doi.org/10.5497/wjp.v4.i1.1

Manuscript File	12462-Review.doc
Answering Reviewers	12462-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	12462-Conflict-of-interest statement.pdf
Copyright License Agreement	12462-Copyright assignment.pdf
Peer-review Report	12462-Peer review(s).pdf
Scientific Misconduct Check	12462-CrossCheck.jpg
Scientific Editor Work List	12462-Scientific editor work list.pdf