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10/21/2026 2:09:39 AM | Browse: 2 | Download: 0
Publication Name World Journal of Hepatology
Manuscript ID 124666
Country Italy
Received
2026-06-26 07:57
Peer-Review Started
2026-06-26 07:58
First Decision by Editorial Office Director
Return for Revision
2026-07-22 06:25
Revised
2026-08-01 14:41
Publication Fee Transferred
Second Decision by Editor
2026-09-20 02:51
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-09-20 10:47
Articles in Press
2026-09-20 10:47
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-09-29 10:07
Publish the Manuscript Online
2026-10-21 02:09
ISSN 1948-5182 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Prospective Study
Article Title Gut microbiome in patients with cirrhosis and clinically significant portal hypertension: A pilot study
Manuscript Source Unsolicited Manuscript
All Author List Giuseppe Colucci, Sonia Stella, Andrea Castagnetti, Laura Di Rito, Martina Lucà, Giulia Tosetti, Roberta D’Ambrosio and Pietro Lampertico
ORCID
Author(s) ORCID Number
Giuseppe Colucci http://orcid.org/0000-0002-4110-459X
Roberta D’Ambrosio http://orcid.org/0000-0003-0019-1153
Pietro Lampertico http://orcid.org/0000-0002-1026-7476
Funding Agency and Grant Number
Corresponding Author Giuseppe Colucci, Associate Research Scientist, MD, Research Assistant Professor, Division of Gastroenterology and Hepatology, IRCCS Fondazione Ca’ Granda Ospedale Maggiore Policlinico, via F. Sforza 28, Milan 20122, Italy. giuseppe.colucci@guest.unimi.it
Key Words Microbiome; Cirrhosis; Portal hypertension; Dysbiosis; Biodiversity
Core Tip The gut-liver axis is affected in cirrhosis with clinically significant portal hypertension and may contribute to disease progression and liver decompensation. In a group of patients recruited in a pilot study, we detected significant differences in the intestinal microbiota and mycobiota compared to healthy controls, including the presence of specific pathobionts. Dietary modifications and the supplementation of specific pre and probiotics may help preventing disease progression in patients with cirrhosis and clinically significant portal hypertension.
Publish Date 2026-10-21 02:09
Citation

Colucci G, Stella S, Castagnetti A, Di Rito L, Lucà M, Tosetti G, D’Ambrosio R, Lampertico P. Gut microbiome in patients with cirrhosis and clinically significant portal hypertension: A pilot study. World J Hepatol 2026; 18(10): 124666

URL https://www.wjgnet.com/1948-5182/full/v18/i10/124666.htm
DOI https://doi.org/10.4254/wjh.124666
Full Article (PDF) WJH-18-124666-with-cover.pdf
CONSORT 2010 Statement 124666-CONSORT-2010-statement.pdf
Manuscript File 124666_Auto_Edited_005505.docx
Answering Reviewers 124666-answering-reviewers.pdf
Audio Core Tip 124666-audio.m4a
Biostatistics Review Certificate 124666-biostatistics-statement.pdf
Clinical Trial Registration Statement 124666-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 124666-conflict-of-interest-statement.pdf
Copyright License Agreement 124666-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 124666-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 124666-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 124666-non-native-speakers.pdf
Peer-review Report 124666-peer-reviews.pdf
Scientific Misconduct Check 124666-scientific-misconduct-check.png
CrossCheck Report 124666-crosscheck-report.pdf