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9/24/2026 12:48:57 AM | Browse: 1 | Download: 0
Publication Name World Journal of Cardiology
Manuscript ID 124700
Country Ukraine
Received
2026-06-23 05:59
Peer-Review Started
2026-06-23 06:00
First Decision by Editorial Office Director
Return for Revision
2026-08-13 07:20
Revised
2026-08-14 16:55
Publication Fee Transferred
Second Decision by Editor
2026-09-08 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-09-08 09:55
Articles in Press
2026-09-08 09:55
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-09-11 13:40
Publish the Manuscript Online
2026-09-24 00:48
ISSN 1949-8462 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Correspondence
Article Title Letter to the Editor: Anchoring composite electrocardiography–heart rate variability indices to a reference standard - the authors’ reply
Manuscript Source Unsolicited Manuscript
All Author List Illya A Chaikovsky, Dmytro O Dziuba, Olga A Kryvova, Kyrylo S Malakhov, Oleksandr P Romanchuk, Borys M Todurov and Оleg A Loskutov
ORCID
Author(s) ORCID Number
Illya A Chaikovsky http://orcid.org/0000-0002-4152-0331
Dmytro O Dziuba http://orcid.org/0000-0002-9979-8889
Olga A Kryvova http://orcid.org/0000-0002-4407-5990
Kyrylo S Malakhov http://orcid.org/0000-0003-3223-9844
Oleksandr P Romanchuk http://orcid.org/0000-0001-6592-2573
Borys M Todurov http://orcid.org/0009-0000-2047-4447
Оleg A Loskutov http://orcid.org/0000-0002-7646-9193
Funding Agency and Grant Number
Corresponding Author Oleksandr P Romanchuk, DM, Full Professor, MD, PhD, Professor, Department of Internal and Family Medicine, Lesya Ukrainka Volyn National University, Bankova Street, 9, Lutsk 43025, Ukraine. romanchuk.oleksandr@vnu.edu.ua
Key Words Percutaneous coronary intervention; Myocardial injury; Electrocardiography; Heart rate variability; Reference standard; Cardiac troponin; Cardiac magnetic resonance; Validation
Core Tip Composite electrocardiography and heart rate variability indices can flag small post-procedural changes that the routine 12-lead electrocardiogram misses, but they cannot separate injury from recovery unless anchored to an accepted reference standard. In this reply we set out how that anchor — paired high-sensitivity troponin and late gadolinium enhancement on cardiac magnetic resonance, with injury pre-specified by the Fourth Universal Definition of Myocardial Infarction — will be built into a larger, prospective, presentation-stratified study. We distinguish the validated construction of the composite indices from the exploratory within-cohort clustering, which still requires independent validation before any clinical use.
Publish Date 2026-09-24 00:48
Citation

Chaikovsky IA, Dziuba DO, Kryvova OA, Malakhov KS, Romanchuk OP, Todurov BM, Loskutov ОA. Letter to the Editor: Anchoring composite electrocardiography–heart rate variability indices to a reference standard - the authors’ reply. World J Cardiol 2026; 18(9): 124700

URL https://www.wjgnet.com/1949-8462/full/v18/i9/124700.htm
DOI https://doi.org/10.4330/wjc.124700
Full Article (PDF) WJC-18-124700-with-cover.pdf
Manuscript File 124700_Auto_Edited_015248.docx
Answering Reviewers 124700-answering-reviewers.pdf
Audio Core Tip 124700-audio.mp3
Conflict-of-Interest Disclosure Form 124700-conflict-of-interest-statement.pdf
Copyright License Agreement 124700-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 124700-non-native-speakers.pdf
Peer-review Report 124700-peer-reviews.pdf
Scientific Misconduct Check 124700-scientific-misconduct-check.png
CrossCheck Report 124700-crosscheck-report.pdf