BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
11/6/2026 1:05:17 AM | Browse: 1 | Download: 1
 |
Received |
|
2026-06-24 01:30 |
|
Peer-Review Started |
|
2026-06-25 23:56 |
 |
First Decision by Editorial Office Director |
|
|
|
Return for Revision |
|
2026-07-07 02:40 |
|
Revised |
|
2026-07-10 10:51 |
|
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2026-08-06 02:38 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2026-08-10 11:00 |
|
Articles in Press |
|
2026-08-10 11:00 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2026-08-31 10:12 |
|
Publish the Manuscript Online |
|
2026-11-06 01:05 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Ophthalmology |
| Manuscript Type |
Editorial |
| Article Title |
PRDX2 and Müller cells in diabetic retinopathy
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Francesco Cappellani, Matteo Capobianco, Antonio M. Vicari and Marco Zeppieri |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Marco Zeppieri, Consultant, MD, PhD, Postdoc, Department of Ophthalmology, University Hospital of Udine, p. le S. Maria della Misericordia 15, Udine 33100, Italy. mark.zeppieri@asufc.sanita.fvg.it |
| Key Words |
Müller glial cells; Diabetic retinopathy; RhoA/ROCK signaling; Peroxiredoxin-2; Redox dysregulation |
| Core Tip |
The emerging role of Müller cell dysfunction anticipating and worsening diabetic retinopathy is increasingly acknowledged. The altered redox balance in Müller glial hyperreactivity triggering the RhoA/ROCK pathway was widely demonstrated by Du et al with peroxiredoxin-2 (PRDX2). This article offers an overview of the PRDX2-related cytoskeletal reorganization and glial proliferation, moreover it suggests a different perspective above the conventional role of antioxidant enzymes and suggests also some future perspective for new targeted therapies to contrast gliosis effects and preserving neurovascular health. |
| Publish Date |
2026-11-06 01:05 |
| Citation |
Cappellani F, Capobianco M, Vicari AM, Zeppieri M. PRDX2 and Müller cells in diabetic retinopathy. World J Diabetes 2026; 17(11): 124773
|
| URL |
https://www.wjgnet.com/1948-9358/full/v17/i11/124773.htm |
| DOI |
https://doi.org/10.4239/wjd.124773 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
