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Articles Published Processes
9/17/2026 5:48:20 AM | Browse: 0 | Download: 0
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Received |
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2026-06-24 07:04 |
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Peer-Review Started |
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2026-06-24 07:04 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-07-21 07:13 |
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Revised |
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2026-07-23 08:16 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-08-12 02:38 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-08-14 10:12 |
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Articles in Press |
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2026-08-14 10:12 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-09-09 10:01 |
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Publish the Manuscript Online |
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2026-09-17 05:48 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Hepatocellular carcinoma with obstructive jaundice: Biliary drainage and multimodal therapy
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Pan Xiao, Ke-Xin Chen, Lian-Lu Jiang and Li Zhang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Lian-Lu Jiang, Chief Physician, Researcher, Department of Hepatobiliary, Pancreatic and Splenic Surgery, First Affiliated Hospital of Hunan College of TCM (Hunan Province Directly Affiliated TCM Hospital), No. 50 Renmin Middle Road, Lusong District, Zhuzhou 412000, Hunan Province, China. jiexiu666@gmail.com |
| Key Words |
Hepatocellular carcinoma; Obstructive jaundice; Bile duct tumor thrombus; Biliary drainage; Transarterial chemoembolization; Hepatic arterial infusion chemotherapy; Immunotherapy; Multidisciplinary management |
| Core Tip |
Patients with hepatocellular carcinoma-related jaundice should first be evaluated for a mechanical obstructive component rather than assumed to have irreversible liver failure. Endoscopic or percutaneous drainage may relieve cholestasis and allow treatment reassessment, but response definitions vary and apparent survival advantages are vulnerable to selection bias. Transarterial chemoembolization has the largest direct post-drainage evidence base; hepatic arterial infusion chemotherapy, radiotherapy, systemic therapy, and transplantation are supported mainly by small retrospective studies, case reports, or extrapolation. Drainage modality and subsequent treatment should be individualized by a multidisciplinary team, with clinical trials preferred whenever feasible. |
| Publish Date |
2026-09-17 05:48 |
| Citation |
Xiao P, Chen KX, Jiang LL, Zhang L. Hepatocellular carcinoma with obstructive jaundice: Biliary drainage and multimodal therapy. World J Hepatol 2026; 18(9): 124789
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| URL |
https://www.wjgnet.com/1948-5182/full/v18/i9/124789.htm |
| DOI |
https://doi.org/10.4254/wjh.124789 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
