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Articles Published Processes
10/12/2026 6:27:05 AM | Browse: 1 | Download: 0
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Received |
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2026-06-24 01:30 |
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Peer-Review Started |
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2026-06-24 09:12 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-07-07 02:38 |
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Revised |
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2026-07-17 20:11 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-08-18 00:10 |
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Second Decision by Editor-in-Chief |
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2026-08-18 02:24 |
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Final Decision by Editorial Office Director |
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2026-08-28 10:23 |
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Articles in Press |
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2026-08-28 10:23 |
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Edit the Manuscript by Language Editor |
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2026-08-31 19:44 |
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Typeset the Manuscript |
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2026-09-23 09:04 |
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Publish the Manuscript Online |
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2026-10-12 06:27 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Obstetrics & Gynecology |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Human pregnancy outcomes after early glucagon-like peptide-1 receptor agonist exposure: A scoping review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ritu Singh, Akriti Singh and Awadhesh Kumar Singh |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ritu Singh, MD, Department of Reproductive Medicine, Horizon Multispecialty Hospital, P-34, C.I.T Road, Kolkata, Kolkata 700014, West Bengal, India. drritusingh73@gmail.com |
| Key Words |
Glucagon-like peptide-1 receptor agonist; Semaglutide; Tirzepatide; Pregnancy; Preconception; Periconception; Congenital malformation; Obesity; Type 2 diabetes; Scoping review |
| Core Tip |
This scoping review maps the full human evidence spectrum on glucagon-like peptide-1 receptor agonist (GLP-1RA) exposure before conception and during early pregnancy, from case reports to meta-analyses. The most important finding is cautiously reassuring: No consistent overall signal of major congenital malformation has emerged after inadvertent early exposure. However, pregnancy loss, termination, hypertensive disorders, preterm birth, fetal growth, and renal/genitourinary signals remain uncertain and highly confounded. Clinicians should reassure after accidental exposure, stop GLP-1RAs once pregnancy is recognized, and avoid planned or continued use during pregnancy until stronger prospective evidence is available. |
| Publish Date |
2026-10-12 06:27 |
| Citation |
Singh R, Singh A, Singh AK. Human pregnancy outcomes after early glucagon-like peptide-1 receptor agonist exposure: A scoping review. World J Diabetes 2026; 17(10): 124799
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| URL |
https://www.wjgnet.com/1948-9358/full/v17/i10/124799.htm |
| DOI |
https://doi.org/10.4239/wjd.124799 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
