Publication Name	World Journal of Clinical Cases
Manuscript ID	1248
Country	Italy

Received	2012-11-25 05:19
Peer-Review Started	2012-11-27 10:05
To Make the First Decision	2013-01-05 12:59
Return for Revision	2013-01-06 15:54
Revised	2013-01-24 00:10
Second Decision	2013-02-06 11:55
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-02-06 12:23
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-02-24 18:55
Typeset the Manuscript	2013-04-03 17:35
Publish the Manuscript Online	2013-04-10 18:57

ISSN	2307-8960 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Medicine, General & Internal
Manuscript Type	Case Report
Article Title	Treatment of a patient with congenital analbuminemia with atorvastatin and albumin infusion
Manuscript Source	Invited Manuscript
All Author List	Maria Del Ben, Francesco Angelico, Lorenzo Loffredo and Francesco Violi
Funding Agency and Grant Number
Corresponding Author	Francesco Angelico, Professor, Clinica Medica I, Sapienza University, Viale del Policlinico 155, 00161 Rome, Italy. francesco.angelico@uniroma1.it
Key Words	Analbuminemia; Hypercholesterolemia; Atorvastatin; Albumin infusion; Endothelial dysfunction
Core Tip	Congenital analbuminemia is characterized by low plasma albumin and compensatory hypercholesterolemia, which may increase cardiovascular risk. We report a case of congenital analbuminemia (1.0 g/dL) in a 38-year-old male with hypercholesterolemia (range: 406-475 mg/dL) and severe arterial dysfunction [no brachial artery flow-mediated dilation (FMD)]. Long-term, cholesterol-lowering treatment with atorvastatin was associated with the appearance of peripheral edema. Two-months of infusion with albumin improved FMD (7%) and reduced serum cholesterol (273 mg/dL). Statin treatment, together with periodical albumin infusions, may contribute to the safe reduction of cardiovascular risk.
Publish Date	2013-04-10 18:57
Citation	Del Ben M, Angelico F, Loffredo L, Violi F. Treatment of a patient with congenital analbuminemia with atorvastatin and albumin infusion. World J Clin Cases 2013; 1(1): 44-48
URL	http://www.wjgnet.com/2307-8960/full/v1/i1/44.htm
DOI	http://dx.doi.org/10.12998/wjcc.v1.i1.44

Full Article (PDF)	WJCC-1-4.pdf
Manuscript File	1248-Review.doc
Answering Reviewers	1248-Answering reviewers.pdf
Copyright License Agreement	1248-Copyright assignment.pdf
Peer-review Report	1248-Peer reveiw.docx
Scientific Editor Work List	1248-Scientific editor work list.doc