BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
10/9/2026 4:02:20 AM | Browse: 8 | Download: 71
 |
Received |
|
2026-06-24 07:38 |
|
Peer-Review Started |
|
2026-06-24 07:39 |
 |
First Decision by Editorial Office Director |
|
|
|
Return for Revision |
|
2026-07-24 01:20 |
|
Revised |
|
2026-08-06 15:46 |
|
Publication Fee Transferred |
|
2026-08-10 09:28 |
|
Second Decision by Editor |
|
2026-08-26 02:52 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2026-08-26 08:59 |
|
Articles in Press |
|
2026-08-26 08:59 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2026-08-30 07:49 |
|
Publish the Manuscript Online |
|
2026-10-09 04:02 |
| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Nutrition & Dietetics |
| Manuscript Type |
Randomized Controlled Trial |
| Article Title |
Early lactase enzyme supplementation: Efficacy to promote growth and feeding tolerance in preterm infants: A randomized controlled trial
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Walaa E M A Morsi, Ayman E Eskander, Mohamed G Mostafa, Zahraa Ezz ElDin, Fatma A Abdel Maksoud and Amira Elrefaee |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Amira Elrefaee, Lecturer, MD, Department of Pediatrics, Faculty of Medicine, Cairo University, Kasr Al Ainy Faculty of Medicine, Al-Manial, Cairo 11956, Al Qāhirah, Egypt. amiraelrefaee@cu.edu.eg |
| Key Words |
Lactase supplementation; Preterm infants; Feeding intolerance; Weight gain; Necrotizing enterocolitis |
| Core Tip |
This randomized, double-blind controlled trial evaluated lactase enzyme supplementation in preterm infants born before 34 weeks of gestation. Lactase supplementation improved feeding tolerance by reducing gastric residuals, abdominal distension, emesis, and diarrhea. It was also associated with improved stool reducing-substance results, higher fecal pH, and greater daily weight gain. In addition, fewer infants developed necrotizing enterocolitis in the lactase group. These findings suggest that lactase supplementation may be a safe and useful adjunct to enteral feeding in preterm infants. |
| Publish Date |
2026-10-09 04:02 |
| Citation |
Morsi WEMA, Eskander AE, Mostafa MG, Ezz ElDin Z, Abdel Maksoud FA, Elrefaee A. Early lactase enzyme supplementation: Efficacy to promote growth and feeding tolerance in preterm infants: A randomized controlled trial. World J Clin Pediatr 2026; 15(4): 124805
|
| URL |
https://www.wjgnet.com/2219-2808/full/v15/i4/124805.htm |
| DOI |
https://doi.org/10.5409/wjcp.124805 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
