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Articles Published Processes
9/8/2026 3:16:27 AM | Browse: 0 | Download: 0
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Received |
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2026-07-08 08:44 |
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Peer-Review Started |
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2026-07-08 08:45 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-07-22 13:05 |
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Revised |
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2026-07-28 13:49 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-09-01 02:40 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-09-01 08:44 |
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Articles in Press |
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2026-09-01 08:44 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-09-03 00:44 |
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Publish the Manuscript Online |
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2026-09-08 03:16 |
| ISSN |
2150-5330 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Carbohydrate antigen 72-4 and tumor-associated glycoprotein 72 - tumor marker: Past, present and future
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Rui-Kyi Ng and Vishal G Shelat |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Vishal G Shelat, Adjunct Associate Professor, Department of General Surgery, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore. vgshelat@gmail.com |
| Key Words |
Carbohydrate antigen 72-4; Tumor-associated glycoprotein 72; Gastric cancer; Tumor markers; Peritoneal carcinomatosis |
| Core Tip |
Carbohydrate antigen 72-4 (CA72-4) refers mainly to the clinical assay or serum readout of circulating tumor-associated glycoprotein 72 (TAG-72)-related antigenic determinants; while TAG-72 refers to the broader TAG target. Gastric cancer remains the main clinical setting for CA72-4, especially in prognosis, recurrence assessment and peritoneal dissemination. Pleural-fluid CA72-4 has high specificity but modest sensitivity for malignant pleural effusion, supporting a rule-in adjunctive role. TAG-72 also links CA72-4 to cytology, immunohistochemistry, molecular imaging and cellular therapy research. Future studies should prioritize assay standardization, disease-specific thresholds, marker kinetics and patient-management outcomes. |
| Publish Date |
2026-09-08 03:16 |
| Citation |
Ng RK, Shelat VG. Carbohydrate antigen 72-4 and tumor-associated glycoprotein 72 - tumor marker: Past, present and future. World J Gastrointest Pathophysiol 2026; 17(3): 125464
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| URL |
https://www.wjgnet.com/2150-5330/full/v17/i3/125464.htm |
| DOI |
https://doi.org/10.4291/wjgp.125464 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
