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Articles Published Processes
10/26/2026 6:39:39 AM | Browse: 0 | Download: 0
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Received |
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2026-07-14 09:01 |
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Peer-Review Started |
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2026-07-14 09:02 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-08-05 06:35 |
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Revised |
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2026-08-18 17:19 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-10-08 02:36 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-10-20 09:34 |
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Articles in Press |
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2026-10-20 09:34 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-10-21 03:16 |
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Publish the Manuscript Online |
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2026-10-26 06:39 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell & Tissue Engineering |
| Manuscript Type |
Minireviews |
| Article Title |
Potential therapeutic applications of antler stem cells and their derivatives
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Yang He, Ji-Ping Li, Chao Ma, Guo-Kun Zhang and Chun-Yi Li |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
32300708, 32470892 |
| Science and Technology Development Plan Project of Jilin Province |
YDZJ202401453ZYTS |
| Jilin Province Medical and Health Talent Special Project |
2025WSZX-JC03 |
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| Corresponding Author |
Chun-Yi Li, PhD, Professor, Institute of Antler Science and Product Technology, Changchun Sci-Tech University, No. 1345 Pudong Road, Changchun 130600, Jilin Province, China. lichunyi1959@163.com |
| Key Words |
Antler stem cells; Regeneration; Extracellular vesicles; Conditioned medium; Bone; Wound healing; Aging; Regenerative medicine |
| Core Tip |
This review highlights antler stem cells (AnSCs) through three main points. First, it examines distinct populations, such as antler blastema progenitor cells and RXFP2-positive periosteal cells, which are related in the context of antler development and regeneration. Second, it differentiates between living-cell transplantation and cell-free derivatives, noting that the latter currently face fewer manufacturing and safety challenges. Lastly, it compares AnSCs with established mesenchymal stromal cell sources, emphasizing advantages such as strong osteochondral activity and renewable sourcing, while also tackling concerns such as immunogenicity, donor variability, and a lack of human clinical evidence. |
| Publish Date |
2026-10-26 06:39 |
| Citation |
He Y, Li JP, Ma C, Zhang GK, Li CY. Potential therapeutic applications of antler stem cells and their derivatives. World J Stem Cells 2026; 18(10): 125616
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| URL |
https://www.wjgnet.com/1948-0210/full/v18/i10/125616.htm |
| DOI |
https://doi.org/10.4252/wjsc.125616 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
