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Articles Published Processes
10/22/2026 2:34:08 AM | Browse: 0 | Download: 0
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Received |
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2026-07-20 09:15 |
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Peer-Review Started |
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2026-07-20 09:16 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-08-04 07:09 |
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Revised |
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2026-08-22 17:22 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-10-08 07:09 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-10-08 08:35 |
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Articles in Press |
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2026-10-08 08:35 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-10-15 01:33 |
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Publish the Manuscript Online |
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2026-10-22 02:34 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biology |
| Manuscript Type |
Minireviews |
| Article Title |
Vitamin-mediated cancer immune reprogramming: Context-dependent mechanisms and translational perspectives
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Qian Zhang, Rong-Hao Yang, Xiao-Rui An and Hao-Cai Chang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
62475076 |
| Guangdong Provincial Department of Education Key Areas Special Project for Regular Higher Education Institutions |
2023ZDZX2022 |
| Youth S&T Talent Support Programme of Guangdong Provincial Association for Science and Technology |
SKXRC2025014 |
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| Corresponding Author |
Hao-Cai Chang, Assistant Professor, PhD, MOE Key Laboratory of Laser Life Science & Institute of Laser Life Science, College of Biophotonics, School of Optoelectronic Science and Engineering, South China Normal University, No. 55 West Zhongshan Avenue, Tianhe District, Guangzhou 510631, Guangdong Province, China. changhc@scnu.edu.cn |
| Key Words |
Vitamins; Immunometabolism; Tumor microenvironment; Immune checkpoint inhibitor therapy; Dendritic cells; Natural killer cells; Precision vitamin immunotherapy |
| Core Tip |
Vitamins are context-dependent immunometabolic regulators reshaping anti-tumor immunity and immune checkpoint inhibitor response beyond simple antioxidant function. This review summarizes mechanistic and translational evidence of vitamins A/B/C/D/E/K in tumor immunity, putting forward three core principles covering dose-dependent immune effects, epigenetic regulatory mechanisms, and biomarker-guided adjuvant application. We propose a precision vitamin-targeted immunotherapy framework combining deficiency correction, standardized supplementation and matched immune background to optimize tumor immunotherapy efficacy. |
| Publish Date |
2026-10-22 02:34 |
| Citation |
Zhang Q, Yang RH, An XR, Chang HC. Vitamin-mediated cancer immune reprogramming: Context-dependent mechanisms and translational perspectives. World J Clin Oncol 2026; 17(10): 125846
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| URL |
https://www.wjgnet.com/2218-4333/full/v17/i10/125846.htm |
| DOI |
https://doi.org/10.5306/wjco.125846 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
