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Articles Published Processes
10/26/2026 6:39:39 AM | Browse: 0 | Download: 0
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Received |
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2026-07-20 09:01 |
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Peer-Review Started |
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2026-07-20 09:02 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-08-24 09:09 |
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Revised |
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2026-08-24 17:03 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-10-12 00:49 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-10-20 09:35 |
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Articles in Press |
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2026-10-20 09:35 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-10-21 02:49 |
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Publish the Manuscript Online |
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2026-10-26 06:39 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Ophthalmology |
| Manuscript Type |
Minireviews |
| Article Title |
Stem cell secretome- and extracellular vesicle-based therapies for retinal pathologies
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Matteo Capobianco, Francesco Cappellani, Ehimare S Enaholo and Marco Zeppieri |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Marco Zeppieri, Consultant, MD, PhD, Postdoc, Department of Ophthalmology, University Hospital of Udine, p. le S. Maria della Misericordia 15, Udine 33100, Italy. mark.zeppieri@asufc.sanita.fvg.it |
| Key Words |
Stem cell secretome; Retinal degeneration; Exosomes; Regenerative medicine; Extracellular vesicles |
| Core Tip |
Stem cell secretome and extracellular vesicles are under exploration as acellular therapeutic approaches for retinal disease. Their biological activity appears to depend largely on the transfer of trophic factors, proteins, lipids, and regulatory RNAs that can influence inflammation, oxidative stress, apoptosis, vascular homeostasis, and neuronal survival. Although the findings reported to date are encouraging, most of the available evidence remains preclinical. Before these products can enter routine retinal care, substantial work is still needed to standardize their production and characterization, define appropriate dosing, establish reliable potency assays, and assess long-term safety. |
| Publish Date |
2026-10-26 06:39 |
| Citation |
Capobianco M, Cappellani F, Enaholo ES, Zeppieri M. Stem cell secretome- and extracellular vesicle-based therapies for retinal pathologies. World J Stem Cells 2026; 18(10): 125852
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| URL |
https://www.wjgnet.com/1948-0210/full/v18/i10/125852.htm |
| DOI |
https://doi.org/10.4252/wjsc.125852 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
