BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
10/13/2026 9:29:22 AM | Browse: 1 | Download: 1
Publication Name World Journal of Clinical Cases
Manuscript ID 126027
Country China
Received
2026-07-23 09:14
Peer-Review Started
2026-07-23 09:14
First Decision by Editorial Office Director
Return for Revision
2026-08-10 06:45
Revised
2026-08-31 14:30
Publication Fee Transferred
2026-09-13 12:40
Second Decision by Editor
2026-10-09 03:30
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-10-09 09:10
Articles in Press
2026-10-09 09:10
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-10-13 01:24
Publish the Manuscript Online
2026-10-13 09:29
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Case Report
Article Title Multicomponent metaplastic breast cancer with four histological components: A case report
Manuscript Source Unsolicited Manuscript
All Author List Ting-Jun Zhao, Shi-Lei Chen, Yun-Long Zhou, Zheng-Jia Jin and Gao-Shi Huang
ORCID
Author(s) ORCID Number
Gao-Shi Huang http://orcid.org/0009-0001-9603-5288
Funding Agency and Grant Number
Corresponding Author Gao-Shi Huang, Department of General Surgery, The First People's Hospital of Wuyi County, No. 2 Nanmen Street, Jinhua 321200, Zhejiang Province, China. 3290029855@qq.com
Key Words Breast; Metaplastic breast cancer; Multicomponent; Triple-negative breast cancer; Case report
Core Tip Metaplastic breast cancer (MMBC) is a rare breast malignancy with poor prognosis and a lack of standardized treatment strategies. We report a rare case of MMBC with three invasive components plus associated ductal carcinoma in situ components, a presentation that is seldom encountered in clinical practice. The tumor exhibits a triple-negative phenotype, a high Ki-67 proliferation index, and TP53 and AKT1 gene mutations. The patient completed 8 cycles of sequential Pirarubicin plus cyclophosphamide followed by docetaxel plus cisplatin adjuvant chemotherapy, with manageable grade 2-3 adverse reactions. No local recurrence or distant metastasis was observed during the 20-month follow-up period. This case provides clinical evidence for diagnosis, individualized therapy, and prognostic evaluation of multicomponent MMBC.
Publish Date 2026-10-13 09:29
Citation

Zhao TJ, Chen SL, Zhou YL, Jin ZJ, Huang GS. Multicomponent metaplastic breast cancer with four histological components: A case report. World J Clin Cases 2026; 14(27): 126027

URL https://www.wjgnet.com/2307-8960/full/v14/i27/126027.htm
DOI https://doi.org/10.12998/wjcc.126027
Full Article (PDF) WJCC-14-126027-with-cover.pdf
CARE Checklist–2016 126027-CARE-Checklist-2016.pdf
Manuscript File 126027_Auto_Edited_020052.docx
Answering Reviewers 126027-answering-reviewers.pdf
Audio Core Tip 126027-audio.wav
Conflict-of-Interest Disclosure Form 126027-conflict-of-interest-statement.pdf
Copyright License Agreement 126027-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 126027-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 126027-non-native-speakers.pdf
Peer-review Report 126027-peer-reviews.pdf
Scientific Misconduct Check 126027-scientific-misconduct-check.png
CrossCheck Report 126027-crosscheck-report.pdf