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4/15/2015 11:01:00 AM | Browse: 1462 | Download: 1900
Publication Name World Journal of Gastroenterology
Manuscript ID 12612
Country/Territory China
Received
2014-07-17 09:34
Peer-Review Started
2014-07-17 17:04
To Make the First Decision
2014-08-15 12:19
Return for Revision
2014-08-22 09:46
Revised
2014-09-04 16:35
Second Decision
2014-10-21 17:40
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-10-21 17:55
Articles in Press
2014-10-21 18:10
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-11-05 17:42
Typeset the Manuscript
2015-03-27 09:19
Publish the Manuscript Online
2015-04-15 11:01
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Meta-Analysis
Article Title Probiotics in Helicobacter pylori eradication therapy: A systematic review and meta-analysis
Manuscript Source Unsolicited Manuscript
All Author List Min-Min Zhang, Wei Qian, Ying-Yi Qin, Jia He and Yu-Hao Zhou
Funding Agency and Grant Number
Funding Agency Grant Number
Ministry of Science and Technology of China 2008ZX10002-007
Ministry of Science and Technology of China 2008ZX10002-018
Ministry of Science and Technology of China 2008ZX10002-025
Leading Talents of Science in Shanghai 2010 (022)
Key Discipline Construction of Evidence-Based Public Health in Shanghai 12GWZX0602
National Science Foundation of China 81373105
Corresponding Author Dr. Yu-Hao Zhou, Department of Rehabilitation Institute, Shanghai Seventh People’s Hospital, No. 358 Datong Road, Pudong New Area, Shanghai 200137, China. zhou_ly@126.com
Key Words Probiotics; Helicobacter pylori; Eradication; Systematic review; Meta-analysis
Core Tip Probiotics have a positive effect on Helicobacter pylori (H. pylori) eradication since these compounds also induce anti-inflammatory and anti-oxidative mechanisms that regulate intestinal microbiota. The benefits of probiotics supplementation in the treatment of antibiotic resistant H. pylori are still unclear due to the lack of supporting evidence. In this meta-analysis of 45 randomized controlled trials involving nearly 6997 individuals, we found that the use of probiotics plus standard therapy was associated with an increase in the H. pylori eradication rate, and a reduction in adverse events resulting from treatment in the general population. However, this therapy did not improve patient compliance.
Publish Date 2015-04-15 11:01
Citation Zhang MM, Qian W, Qin YY, He J, Zhou YH. Probiotics in Helicobacter pylori eradication therapy: A systematic review and meta-analysis. World J Gastroenterol 2015; 21(14): 4345-4357
URL http://www.wjgnet.com/1007-9327/full/v21/i14/4345.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i14.4345
Full Article (PDF) WJG-21-4345.pdf
Full Article (Word) WJG-21-4345.doc
Manuscript File 12612-Review.doc
Answering Reviewers 12312-Answering reviewers.pdf
Copyright License Agreement 12612-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 12612-Language certificate.pdf
Peer-review Report 12612-Peer review(s).pdf
Scientific Misconduct Check 12612-CrossCheck.jpg
Scientific Editor Work List 12612-Scientific editor work list.pdf