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Articles Published Processes
4/15/2015 11:01:00 AM | Browse: 1592 | Download: 2186
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Received |
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2014-07-17 09:34 |
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Peer-Review Started |
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2014-07-17 17:04 |
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To Make the First Decision |
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2014-08-15 12:19 |
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Return for Revision |
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2014-08-22 09:46 |
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Revised |
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2014-09-04 16:35 |
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Second Decision |
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2014-10-21 17:40 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-10-21 17:55 |
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Articles in Press |
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2014-10-21 18:10 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2014-11-05 17:42 |
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Typeset the Manuscript |
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2015-03-27 09:19 |
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Publish the Manuscript Online |
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2015-04-15 11:01 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Probiotics in Helicobacter pylori eradication therapy: A systematic review and meta-analysis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Min-Min Zhang, Wei Qian, Ying-Yi Qin, Jia He and Yu-Hao Zhou |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Ministry of Science and Technology of China |
2008ZX10002-007 |
| Ministry of Science and Technology of China |
2008ZX10002-018 |
| Ministry of Science and Technology of China |
2008ZX10002-025 |
| Leading Talents of Science in Shanghai 2010 (022) |
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| Key Discipline Construction of Evidence-Based Public Health in Shanghai |
12GWZX0602 |
| National Science Foundation of China |
81373105 |
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| Corresponding Author |
Dr. Yu-Hao Zhou, Department of Rehabilitation Institute, Shanghai Seventh People’s Hospital, No. 358 Datong Road, Pudong New Area, Shanghai 200137, China. zhou_ly@126.com |
| Key Words |
Probiotics; Helicobacter pylori; Eradication; Systematic review; Meta-analysis |
| Core Tip |
Probiotics have a positive effect on Helicobacter pylori (H. pylori) eradication since these compounds also induce anti-inflammatory and anti-oxidative mechanisms that regulate intestinal microbiota. The benefits of probiotics supplementation in the treatment of antibiotic resistant H. pylori are still unclear due to the lack of supporting evidence. In this meta-analysis of 45 randomized controlled trials involving nearly 6997 individuals, we found that the use of probiotics plus standard therapy was associated with an increase in the H. pylori eradication rate, and a reduction in adverse events resulting from treatment in the general population. However, this therapy did not improve patient compliance. |
| Publish Date |
2015-04-15 11:01 |
| Citation |
Zhang MM, Qian W, Qin YY, He J, Zhou YH. Probiotics in Helicobacter pylori eradication therapy: A systematic review and meta-analysis. World J Gastroenterol 2015; 21(14): 4345-4357 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i14/4345.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i14.4345 |
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