Publication Name	World Journal of Psychiatry
Manuscript ID	12615
Country	Brazil

Received	2014-07-19 12:48
Peer-Review Started	2014-07-19 20:35
To Make the First Decision	2014-10-14 17:37
Return for Revision	2014-10-20 08:19
Revised	2014-11-21 08:37
Second Decision	2014-12-10 11:28
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-12-17 16:19
Articles in Press	2014-12-17 16:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-03-12 18:01
Publish the Manuscript Online	2015-03-23 14:43

ISSN	2220-3206 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Psychiatry
Manuscript Type	Review
Article Title	Postpartum depression: A systematic review of the genetics involved
Manuscript Source	Invited Manuscript
All Author List	Tiago Castro e Couto, Mayra Yara Martins Brancaglion, António Alvim-Soares, Lafaiete Moreira, Frederico Duarte Garcia, Rodrigo Nicolato, Regina Amélia Lopes P Aguiar, Henrique Vitor Leite and Humberto Corrêa
Funding Agency and Grant Number	Funding Agency Grant Number Fundação de Amparo à Pesquisa do Estado de Minas Gerais to Humberto Corrêa Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) to Humberto Corrêa
Corresponding Author	Tiago Castro e Couto, MD, Postgraduate Program in Molecular Medicine, School of Medicine, Universidade Federal de Minas Gerais, Alfredo Balena Av, 190/240 Santa Efigênia, Belo Horizonte 30130100, MG, Brazil. tiagocastrocouto@gmail.com
Key Words	Genetics; Single nucleotide polymorphisms; Molecular; Postpartum depression; Genes
Core Tip	5HTT and 5HTTLPR were the most studied gene and polymorphism, respectively. 5HTTLPR is associated with postpartum depression (PPD) in the majority of papers, but epigenetics must be considered. TPH1 and TPH2 polymorphisms are related to peripartum depression. COMT and MAOA polymorphisms were also risk factors for PPD. Once again, only when epigenetic was analyzed, an association with BDNF polymorphism was possible. MTHFR, CYP2D6 and PER2 polymorphisms were not related to this mood disorder. Polymorphisms of oxytocin, steroids and estrogen genes were positively correlated with PPD.
Publish Date	2015-03-23 14:43
Citation	Couto TC, Brancaglion MYM, Alvim-Soares A, Moreira L, Garcia FD, Nicolato R, Aguiar RAL, Leite HV, Corrêa H. Postpartum depression: A systematic review of the genetics involved. World J Psychiatr 2015; 5(1): 103-111
URL	http://www.wjgnet.com/2220-3206/full/v5/i1/103.htm
DOI	http://dx.doi.org/10.5498/wjp.v5.i1.103

Full Article (PDF)	WJP-5-103.pdf
Full Article (Word)	WJP-5-103.doc
Manuscript File	12615-Review.doc
Answering Reviewers	12615-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	12615-Conflict-of-interest statement.pdf
Copyright License Agreement	12615-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	12615-Language certificate.pdf
Peer-review Report	12615-Peer review(s).pdf
Scientific Misconduct Check	12615-CorssCheck.jpg
Scientific Editor Work List	12615-Scientific editor work list.pdf