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Publication Name World Journal of Clinical Cases
Manuscript ID 126184
Country United States
Received
2026-07-31 03:28
Peer-Review Started
2026-08-05 03:37
First Decision by Editorial Office Director
Return for Revision
2026-09-09 06:55
Revised
2026-10-02 17:29
Publication Fee Transferred
Second Decision by Editor
2026-10-22 07:01
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-10-22 09:03
Articles in Press
2026-10-22 09:03
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-10-23 01:36
Publish the Manuscript Online
2026-10-23 08:55
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Case Report
Article Title Persistent alpha-fetoprotein elevation in patients without viral hepatitis, cirrhosis, hepatocellular carcinoma: A report of six cases and literature review
Manuscript Source Unsolicited Manuscript
All Author List Tung Huynh, Kim Huynh, Joey Zhou and Ke-Qin Hu
ORCID
Author(s) ORCID Number
Tung Huynh http://orcid.org/0000-0002-0673-5513
Ke-Qin Hu http://orcid.org/0000-0003-3377-6553
Funding Agency and Grant Number
Corresponding Author Ke-Qin Hu, Director, FAASLD, MD, Professor, Division of Gastroenterology and Hepatology, University of California Irvine, School of Medicine, 101 The City Drive, Building 22C, Room 1503, Orange, CA 92868, United States. kqhu@uci.edu
Key Words Alpha-fetoprotein; Alpha-fetoprotein elevation; Viral hepatitis; Cirrhosis; Hepatocellular carcinoma; Case report
Core Tip This case series presents 6 cases of mild, persistent, and stable alpha-fetoprotein elevation in the absence of active liver injury, advanced hepatic fibrosis (or cirrhosis), or neoplasms, with a mean follow-up of 48 months. This is a unique and benign clinical presentation that has not been thoroughly described or previously reported.
Publish Date 2026-10-23 08:55
Citation

Huynh T, Huynh K, Zhou J, Hu KQ. Persistent alpha-fetoprotein elevation in patients without viral hepatitis, cirrhosis, hepatocellular carcinoma: A report of six cases and literature review. World J Clin Cases 2026; 14(28): 126184

URL https://www.wjgnet.com/2307-8960/full/v14/i28/126184.htm
DOI https://doi.org/10.12998/wjcc.126184
Full Article (PDF) WJCC-14-126184-with-cover.pdf
CARE Checklist–2016 126184-CARE-Checklist-2016.pdf
Manuscript File 126184_Auto_Edited_022154.docx
Answering Reviewers 126184-answering-reviewers.pdf
Audio Core Tip 126184-audio.m4a
Conflict-of-Interest Disclosure Form 126184-conflict-of-interest-statement.pdf
Copyright License Agreement 126184-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 126184-informed-consent-statement.pdf
Peer-review Report 126184-peer-reviews.pdf
Scientific Misconduct Check 126184-scientific-misconduct-check.png
CrossCheck Report 126184-crosscheck-report.pdf