Publication Name	World Journal of Hematology
Manuscript ID	12627
Country	Japan

Received	2014-07-18 08:39
Peer-Review Started	2014-07-18 11:35
To Make the First Decision	2014-08-28 14:46
Return for Revision	2014-09-05 17:16
Revised	2014-09-20 07:02
Second Decision	2015-03-09 09:15
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-03-18 16:28
Articles in Press	2015-03-18 16:28
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-04-23 14:56
Publish the Manuscript Online	2015-04-29 14:35

ISSN	2218-6204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Hematology
Manuscript Type	Case Report
Article Title	Intravascular proliferating anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma
Manuscript Source	Unsolicited Manuscript
All Author List	Kohei Shiroshita, Jun-ichiro Kida, Kensuke Matsumoto, Makiko Uemura, Genji Yamaoka, Yumi Miyai, Reiji Haba and Osamu Imataki
Funding Agency and Grant Number
Corresponding Author	Dr. Osamu Imataki, Division of Hematology and Stem Cell Transplantation, Department of Internal Medicine, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0793, Japan. oima@med.kagawa-u.ac.jp
Key Words	Malignant lymphoma; Cytotoxic molecule; Intravascular lymphoma; Anaplastic lymphoma kinase; Anaplastic large-cell lymphoma
Core Tip	Intravascular lymphoma (IVL), known as a mature B-cell neoplasm that proliferates intravascularly, is established as an independent clinical entity in the World Health Organization classification. Our patient’s case suggests that IVL is one of the characteristic proliferation patterns commonly seen in lymphomas including B- and T-cell neoplasms, anaplastic large-cell lymphoma, and more. We speculate that the function of the original lymphocytes (T or B cells) designates the tumor biology of IVL. Intravascular proliferation is determined by a lack of adhesion molecules. We suspect that the biological aggressiveness would be modified by other characteristic phenotypes such as anaplastic lymphoma kinase, CD30, and CD56.
Publish Date	2015-04-29 14:35
Citation	Shiroshita K, Kida J, Matsumoto K, Uemura M, Yamaoka G, Miyai Y, Haba R, Imataki O. Intravascular proliferating anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma. World J Hematol 2015; 4(2): 10-15
URL	http://www.wjgnet.com/2218-6204/full/v4/i2/10.htm
DOI	http://dx.doi.org/10.5315/wjh.v4.i2.10

Full Article (PDF)	WJH-4-10.pdf
Full Article (Word)	WJH-4-10.doc
Manuscript File	12627-Review.docx
Answering Reviewers	12627-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	12627-Conflict-of-interest statement.pdf
Copyright License Agreement	12627-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	12627-Language certificate.pdf
Peer-review Report	12627-Peer-review(s).pdf
Scientific Misconduct Check	12627-Scientific misconduct check.pdf
Scientific Editor Work List	12627-Scientific editor work list.pdf