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9/18/2026 8:52:43 AM | Browse: 0 | Download: 0
Publication Name World Journal of Clinical Cases
Manuscript ID 126744
Country Brazil
Received
2026-08-13 06:50
Peer-Review Started
2026-08-13 06:51
First Decision by Editorial Office Director
Return for Revision
2026-08-25 06:22
Revised
2026-09-07 19:43
Publication Fee Transferred
Second Decision by Editor
2026-09-16 07:45
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-09-16 09:48
Articles in Press
2026-09-16 09:48
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-09-18 01:23
Publish the Manuscript Online
2026-09-18 08:52
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Case Report
Article Title Acute liver failure temporally associated with intensive consumption of Plantago major tea: A case report
Manuscript Source Invited Manuscript
All Author List Raul V Ponte, Anderson A Faria, Ludmila R Guedes, Isabela S Yamashiro, Maria L Macedo, Maria C Lima, Priscila F Souza, Paula V Vidigal, Francisco G Penna and João B Sancio
ORCID
Author(s) ORCID Number
Raul V Ponte http://orcid.org/0009-0007-5424-3533
Anderson A Faria http://orcid.org/0000-0002-7962-7396
Ludmila R Guedes http://orcid.org/0000-0002-2524-1615
Isabela S Yamashiro http://orcid.org/0009-0000-8689-6896
Maria L Macedo http://orcid.org/0009-0009-8242-3181
Maria C Lima http://orcid.org/0009-0009-3873-0520
Priscila F Souza http://orcid.org/0000-0003-2777-3268
Paula V Vidigal http://orcid.org/0000-0002-7003-5159
Francisco G Penna http://orcid.org/0000-0002-2338-5367
João B Sancio http://orcid.org/0000-0001-8238-5095
Funding Agency and Grant Number
Corresponding Author Raul V Ponte, MD, Department of Abdominal Transplant Surgery, Fortaleza General Hospital, 900 Riachuelo St, Fortaleza 60822265, Ceara, Brazil. rppp@live.com
Key Words Plantago major; Herb-induced liver injury; Acute liver failure; Liver transplantation; Case report
Core Tip This case describes acute liver failure temporally associated with intensive consumption of Plantago major tea in a previously healthy 44-year-old woman. After consuming approximately 2 L/day of prepared infusion for 15 consecutive days, she developed progressive hepatic dysfunction and grade III hepatic encephalopathy, ultimately requiring urgent liver transplantation. Explant histology demonstrated nonspecific massive hepatic necrosis and marked cholestasis. Although the temporal relationship raises suspicion for herb-induced liver injury, causality cannot be definitively established because the herbal preparation was not botanically authenticated or chemically analyzed.
Publish Date 2026-09-18 08:52
Citation

Ponte RV, Faria AA, Guedes LR, Yamashiro IS, Macedo ML, Lima MC, Souza PF, Vidigal PV, Penna FG, Sancio JB. Acute liver failure temporally associated with intensive consumption of Plantago major tea: A case report. World J Clin Cases 2026; 14(26): 126744

URL https://www.wjgnet.com/2307-8960/full/v14/i26/126744.htm
DOI https://doi.org/10.12998/wjcc.126744
Full Article (PDF) WJCC-14-126744-with-cover.pdf
CARE Checklist–2016 126744-CARE-Checklist-2016.pdf
Manuscript File 126744_Auto_Edited_014742.docx
Answering Reviewers 126744-answering-reviewers.pdf
Audio Core Tip 126744-audio.m4a
Conflict-of-Interest Disclosure Form 126744-conflict-of-interest-statement.pdf
Copyright License Agreement 126744-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 126744-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 126744-non-native-speakers.pdf
Peer-review Report 126744-peer-reviews.pdf
Scientific Misconduct Check 126744-scientific-misconduct-check.png
CrossCheck Report 126744-crosscheck-report.pdf