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Publication Name World Journal of Stem Cells
Manuscript ID 1268
Country/Territory France
Received
2012-11-27 14:08
Peer-Review Started
2012-11-28 15:34
To Make the First Decision
2012-12-13 12:33
Return for Revision
2012-12-13 17:30
Revised
2013-05-22 14:23
Second Decision
2013-08-29 07:53
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-08-29 09:50
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-09-17 09:12
Publish the Manuscript Online
2013-10-31 14:50
ISSN 1948-0210 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Radiology, Nuclear Medicine and Medical Imaging
Manuscript Type Frontier
Article Title New insights for pelvic radiation disease treatment: Multipotent stromal cell is a promise mainstay treatment for the restoration of abdominopelvic severe chronic damages induced by radiotherapy
Manuscript Source Invited Manuscript
All Author List Alain Chapel, Sabine Francois, Luc Douay, Marc Benderitter and Jan Voswinkel
Funding Agency and Grant Number
Corresponding author Alain Chapel, PhD, Radiological Protection and Human Health Division, Institute of Radiological Protection and Nuclear Safety, PRP-HOM/SRBE/Laboratory of Radiopathology and Experimental Therapy, BP17, 92262 Fontenay-aux-Roses, France. alain.chapel@irsn.fr
Keywords Cell therapy; Radiotherapy; Irradiation; Stem cells; Multipotent stromal cells; Mesenchymal stem cells; Clinical trial
Core Tip Multipotent stromal cells (MSCs) provide a long-term effect in inhibition of chronic inflammation and a fistulisation, arrest of hemorrhagic syndromes for the hemorrhagic cystitis. MSCs are successfully used to treat the late effects of radiotherapies for breast cancer and radiodermatitis. Their efficiency was also demonstrated on pain reduction. Concerning clinical trials to cure abdominal late severe damages of radiotherapy, one compassionate trial has demonstrated the feasibility of cell therapy treatment for patients overdosed.
Publish Date 2013-10-31 14:50
Citation Chapel A, Francois S, Douay L, Benderitter M, Voswinkel J. New insights for pelvic radiation disease treatment: Multipotent stromal cell is a promise mainstay treatment for the restoration of abdominopelvic severe chronic damages induced by radiotherapy. World J Stem Cells 2013; 5(4): 106-111
Url http://www.wjgnet.com/1948-0210/full/v5/i4/106.htm
DOI http://dx.doi.org/10.4252/wjsc.v5.i4.106
Full Article (PDF) WJSC-5-106.pdf
Manuscript File 1268-Review.doc
Answering Reviewers 1268-Answering reviewers.pdf
Copyright License Agreement 1268-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 1268-Language certificate.pdf
Peer-review Report 1268-Peer reviews.pdf
Scientific Editor Work List 1268-Scientific editor work list.doc