9/28/2014 2:57:00 PM | Browse: 1233 | Download: 1309
Publication Name | World Journal of Stem Cells |
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Manuscript ID | 12708 |
Country | Germany |
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ISSN | 1948-0210 (online) |
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Open Access | |
Copyright | |
Article Reprints | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247 |
Permissions | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207 |
Publisher | Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website | http://www.wjgnet.com |
Category | Cell Biology |
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Manuscript Type | Minireviews |
Article Title | Impact of parathyroid hormone on bone marrow-derived stem cell mobili-zation and migration |
Manuscript Source | Invited Manuscript |
All Author List | Bruno C Huber, Ulrich Grabmaier and Stefan Brunner |
Funding Agency and Grant Number | |
Corresponding Author | Dr. med. Stefan Brunner, Department of Internal Medcine I, Ludwig-Maximilians-University, Campus Grosshadern, Marchioninistr. 15, D-81377 Munich, Germany. stefan.brunner@med.uni-muenchen.de |
Key Words | Parathyroid hormone; Stem cells; Bone marrow; Mobilization; Migration |
Core Tip | Parathyroid hormone (PTH) is the principal regulator of calcium homeostasis in the human body and controls bone metabolism. Besides to its physiological role in bone remodelling PTH has been demonstrated to influence and expand the bone marrow stem cell niche as well as to induce mobilization of progenitor cells from the bone marrow into the bloodstream. This novel function of PTH on modulating the activity of the stem cell niche in the bone marrow as well as on mobilization and regeneration of bone marrow–derived progenitor cells offers new therapeutic options in bone marrow and stem cell transplantation as well as in the field of ischemic disorders. |
Publish Date | 2014-09-28 14:56 |
Citation | Huber BC, Grabmaier U, Brunner S. Impact of parathyroid hormone on bone marrow-derived stem cell mobilization and migration. World J Stem Cells 2014; 6(5): 637-643 |
URL | http://www.wjgnet.com/1948-0210/full/v6/i5/637.htm |
DOI | http://dx.doi.org/10.4252/wjsc.v6.i5.637 |
Full Article (PDF) | WJSC-6-637.pdf |
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Full Article (Word) | WJSC-6-637.doc |
Manuscript File | 12708-Review.docx |
Answering Reviewers | 12708-Answering reviewers.pdf |
Copyright License Agreement | 12708-Copyright assignment.PDF |
Peer-review Report | 12708-Peer review(s).pdf |
Scientific Misconduct Check | 12708-CrossCheck.jpg |
Scientific Editor Work List | 12708-Scientific editor work list.pdf |