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11/11/2026 5:49:18 AM | Browse: 1 | Download: 1
Publication Name World Journal of Gastroenterology
Manuscript ID 127120
Country South Korea
Received
2026-08-24 02:26
Peer-Review Started
2026-08-24 02:27
First Decision by Editorial Office Director
Return for Revision
2026-09-09 07:15
Revised
2026-09-22 14:05
Publication Fee Transferred
2026-10-10 06:46
Second Decision by Editor
2026-10-29 07:08
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-10-29 10:33
Articles in Press
2026-10-29 10:33
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-11-04 14:40
Publish the Manuscript Online
2026-11-11 05:49
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Prospective Study
Article Title Clinicopathologic and biomolecular features of interval colorectal cancers in Korean patients: A KASID multicenter prospective study
Manuscript Source Unsolicited Manuscript
All Author List Joo Hye Song, Jeong Eun Shin, Dae Sung Kim, Yoo Jin Lee, Hee Chan Yang, Kyeong Ok Kim, Jae Hyun Kim, Gyeong Hoon Kang, Sung Ryul Shim and Kyu Chan Huh
ORCID
Author(s) ORCID Number
Joo Hye Song http://orcid.org/0000-0002-1166-0085
Dae Sung Kim http://orcid.org/0000-0002-4881-7883
Yoo Jin Lee http://orcid.org/0000-0003-1799-0146
Hee Chan Yang http://orcid.org/0000-0001-9847-5343
Kyeong Ok Kim http://orcid.org/0000-0001-5799-7436
Gyeong Hoon Kang http://orcid.org/0000-0003-2380-6675
Kyu Chan Huh http://orcid.org/0000-0003-3746-8419
Funding Agency and Grant Number
Funding Agency Grant Number
National Research Foundation of Korea NRF-2017R1A2B2006514
Corresponding Author Kyu Chan Huh, Department of Internal Medicine, Konyang University Hospital, Konyang University College of Medicine, 158 Gwanjeodong-ro, Seo-gu, Daejeon 03050, South Korea. kchuh@kyuh.ac.kr
Key Words Interval colorectal neoplasm; Etiology; Colonoscopy; CpG island methylator phenotype; Asia
Core Tip This is the first study regarding the clinicopathological and biomolecular features of Korean patients with interval colorectal cancers (CRC). In our study, interval CRC were more common in males and located in the left colon, consistent with previous Asian, but in contrast to Western studies. The risk factors associated with survival were advanced stages and CpG island methylator phenotype (CIMP) (+). On the other hand, microsatellite instability (MSI) and BRAF (+) were protective factors for survival. Similar to western studies, CIMP was higher in interval CRCs. However, MSI, and BRAF mutations were not higher in interval CRCs, than sporadic CRCs, in contrast to Western studies.
Publish Date 2026-11-11 05:49
Citation

Song JH, Shin JE, Kim DS, Lee YJ, Yang HC, Kim KO, Kim JH, Kang GH, Shim SR, Huh KC. Clinicopathologic and biomolecular features of interval colorectal cancers in Korean patients: A KASID multicenter prospective study. World J Gastroenterol 2027; 33(2): 127120

URL https://www.wjgnet.com/1007-9327/full/v33/i2/127120.htm
DOI https://doi.org/10.3748/wjg.127120
Full Article (PDF) WJG-33-127120-with-cover.pdf