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2/5/2015 2:02:00 PM | Browse: 852 | Download: 762
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Received |
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2014-07-24 08:34 |
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Peer-Review Started |
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2014-07-24 15:45 |
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To Make the First Decision |
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2014-08-14 14:56 |
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Return for Revision |
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2014-08-15 17:29 |
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Revised |
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2014-08-26 02:29 |
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Second Decision |
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2014-11-10 15:40 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2014-11-10 15:58 |
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Articles in Press |
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2014-11-10 15:59 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-01-30 09:41 |
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Publish the Manuscript Online |
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2015-02-05 14:02 |
| ISSN |
2220-3176 (online) |
| Open Access |
This article is an open-access article which was
selected by an in-house editor and fully peer-reviewed by external
reviewers. It is distributed in accordance with the Creative
Commons Attribution Non Commercial (CC BY-NC 4.0) license,
which permits others to distribute, remix, adapt, build upon this
work non-commercially, and license their derivative works on
different terms, provided the original work is properly cited and
the use is non-commercial. See: http://creativecommons.org/
licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing
Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Minireviews |
| Article Title |
Pneumococcal disease in adult solid organ transplantationrecipients
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Cristina Roca-Oporto, María Eugenia Pachón-Ibañez, Jerónimo Pachón and Elisa Cordero |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Ministerio de Economíay Competitividad |
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| European Development Regional Fund |
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| Spanish Network for the Research in Infectious Diseases |
REIPI RD12/00015/0001 |
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| Corresponding Author |
efficacy is variable. Booster strategy with 7-valent
pneumococcal conjugate vaccine has not shown
benefit in this population. Despite its relevance, robust
evidence on pneumococcal disease in organ transplant
recipients is lacking. New strategies for improving the
protection of SOT recipients are warranted. |
| Key Words |
Transplantation; Pneumococcal infections; Pneumococcal serotypes; Nasopharyngeal carriage; Pneumococcal vaccine |
| Core Tip |
Streptococcus pneumoniae causes substantial
morbidity and mortality in solid organ transplant (SOT)
recipients, ranging from non-invasive to invasive
diseases, with a 12-fold risk of invasive pneumococcal
disease higher than in non-immunocompromised
patients. Pneumococcal vaccination is recommended
for all SOT recipients with 23-valent pneumococcal
polysaccharides vaccine. Although immunological rate
response is appropriate, it is lower than in the rest of
the population, decreases with time, and its clinical efficacy is variable. Booster strategy with 7-valent
pneumococcal conjugate vaccine has not shown
benefit in this population. Despite its relevance, robust
evidence on pneumococcal disease in organ transplant
recipients is lacking. New strategies for improving the
protection of SOT recipients are warranted. |
| Publish Date |
2015-02-05 14:02 |
| Citation |
Roca-Oporto C, Pachón-Ibañez ME, Pachón J, Cordero E.
Pneumococcal disease in adult solid organ transplantation
recipients. World J Clin Infect Dis 2015; 5(1): 1-10 |
| URL |
http://www.wjgnet.com/2220-3176/full/v5/i1/1.htm |
| DOI |
http://dx.doi.org/10.5495/wjcid.v5.i1.1 |
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