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Publication Name World Journal of Gastroenterology
Manuscript ID 127449
Country China
Received
2026-09-02 08:35
Peer-Review Started
2026-09-02 08:36
First Decision by Editorial Office Director
Return for Revision
2026-09-28 03:29
Revised
2026-10-05 11:06
Publication Fee Transferred
Second Decision by Editor
2026-10-14 06:11
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-10-14 08:37
Articles in Press
2026-10-14 08:37
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-10-16 05:50
Publish the Manuscript Online
2026-10-20 03:52
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Global epidemiology of metabolic dysfunction-associated steatotic liver disease: 2026 update
Manuscript Source Invited Manuscript
All Author List Tie Xiao, Nicholas WS Chew, Giovanni Targher, Christopher D Byrne, Gregory YH Lip, Xiao-Dong Zhou and Ming-Hua Zheng
ORCID
Author(s) ORCID Number
Tie Xiao http://orcid.org/0009-0007-5630-8759
Nicholas WS Chew http://orcid.org/0000-0002-0640-0430
Giovanni Targher http://orcid.org/0000-0002-4325-3900
Christopher D Byrne http://orcid.org/0000-0001-6322-7753
Gregory YH Lip http://orcid.org/0000-0002-7566-1626
Xiao-Dong Zhou http://orcid.org/0000-0002-8534-0818
Ming-Hua Zheng http://orcid.org/0000-0003-4984-2631
Funding Agency and Grant Number
Corresponding Author Ming-Hua Zheng, MAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, No. 2 Fuxue Lane, Wenzhou 325000, Zhejiang Province, China. zhengmh@wmu.edu.cn
Key Words Metabolic dysfunction-associated steatotic liver disease; Metabolic dysfunction-associated steatohepatitis; Epidemiology; Comorbidity; Hepatic and extrahepatic outcomes; Screening; Prevention
Core Tip The epidemiology of metabolic dysfunction-associated steatotic liver disease (MASLD) is rapidly evolving, driven by a rising global burden and shifting patterns across populations. MASLD is no longer viewed as a simple liver-specific disease but as a condition associated with a broad spectrum of hepatic and extrahepatic complications. Advances in non-invasive diagnostics and new pharmacotherapies are reshaping approaches to disease detection and management. This narrative review summarizes recent updates on MASLD epidemiology and discusses their implications for clinical practice.
Publish Date 2026-10-20 03:52
Citation

Xiao T, Chew NW, Targher G, Byrne CD, Lip GY, Zhou XD, Zheng MH. Global epidemiology of metabolic dysfunction-associated steatotic liver disease: 2026 update. World J Gastroenterol 2026; 32(46): 127449

URL https://www.wjgnet.com/1007-9327/full/v32/i46/127449.htm
DOI https://doi.org/10.3748/wjg.127449
Full Article (PDF) WJG-32-127449-with-cover.pdf
Manuscript File 127449_Auto_Edited_055129.docx
Answering Reviewers 127449-answering-reviewers.pdf
Audio Core Tip 127449-audio.m4a
Conflict-of-Interest Disclosure Form 127449-conflict-of-interest-statement.pdf
Copyright License Agreement 127449-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 127449-non-native-speakers.pdf
Peer-review Report 127449-peer-reviews.pdf
Scientific Misconduct Check 127449-scientific-misconduct-check.png
CrossCheck Report 127449-crosscheck-report.pdf