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12/13/2014 7:02:00 PM | Browse: 509 | Download: 701
Publication Name World Journal of Diabetes
Manuscript ID 12750
Country of Manuscript Source Japan
Received
2014-07-24 18:57
Peer-Review Started
2014-07-25 21:19
To Make the First Decision
2014-08-14 14:56
Return for Revision
2014-08-17 12:38
Revised
2014-08-21 14:08
Second Decision
2014-10-27 16:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-10-27 17:12
Articles in Press
2014-10-27 17:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-11-27 17:00
Publish the Manuscript Online
2014-12-13 19:01
ISSN 1948-9358 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Endocrinology and Metabolism
Manuscript Type Minireviews
Article Title Possible contribution of (pro)renin receptor to development of gestational diabetes mellitus
Manuscript Source Invited Manuscript
All Author List Kanako Bokuda and Atsuhiro Ichihara
Funding Agency and Grant Number
Corresponding author Kanako Bokuda, MD, Department of Medicine Ⅱ, Institute of Endocrinology and Hypertension, Tokyo Women’s Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan. mkanakom31@yahoo.co.jp
Keywords (Pro)renin receptor; Gestational diabetes mellitus; Embryonic growth; Renin-angiotensin system; Vacuolar H+-ATPase; Wnt signaling
Core Tip Prorenin receptor [(P)RR] binds (pro)renin, and leads to the activation of tissue renin-angiotensin system and intracellular signalings. It also plays an important role as vacuolar H+-ATPase associated protein, involving in Wnt signaling. Elevated plasma soluble (P)RR [s(P)RR] levels in the early stage of pregnancies are associated with higher incidence of gestational diabetes mellitus (GDM) during the third trimester. Also, elevated s(P)RR levels in cord blood, associated with a lower small for gestational age birth likelihood, suggesting the involvement of (P)RR in embryo’s growth. Here we attempt to elucidate the possible pathophysiological roles of the (P)RR in GDM.
Publish Date 2014-12-13 19:01
Citation Bokuda K, Ichihara A. Possible contribution of (pro)renin receptor to development of gestational diabetes mellitus. World J Diabetes 2014; 5(6): 912-916
Url http://www.wjgnet.com/1948-9358/full/v5/i6/912.htm
DOI http://dx.doi.org/10.4239/wjd.v5.i6.912
Full Article (PDF) WJD-5-912.pdf
Full Article (Word) WJD-5-912.doc
Manuscript File 12750-Review.docx
Answering Reviewers 12750-Answering reviewers.pdf
Copyright License Agreement 12750-Copyright assignment.pdf
Peer-review Report 12750-Peer review(s).pdf
Scientific Misconduct Check 12750-CrossCheck.jpg
Scientific Editor Work List 12750-Scientific editor work list.pdf