Publication Name	World Journal of Gastroenterology
Manuscript ID	12764
Country	Brazil

Received	2014-07-25 09:11
Peer-Review Started	2014-07-25 10:47
To Make the First Decision	2014-08-27 19:17
Return for Revision	2014-09-03 17:11
Revised
Second Decision	2015-06-08 08:06
Accepted by Journal Editor-in-Chief	2015-06-08 19:22
Accepted by Executive Editor-in-Chief	2015-06-16 11:11
Articles in Press	2015-06-16 11:11
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-07-15 03:39
Typeset the Manuscript	2015-08-11 16:18
Publish the Manuscript Online	2015-08-20 13:37

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Genetics & Heredity
Manuscript Type	Observational Study
Article Title	Presence of c.3956delC mutation in familial adenomatous polyposis patients from Brazil
Manuscript Source	Unsolicited Manuscript
All Author List	Caroline Aquino Moreira-Nunes, Diego di Felipe Ávila Alcântara, Sérgio Figueiredo Lima-Júnior, Sandro Roberto de Araújo Cavalléro, Juan Antonio Rey, Giovanny Rebouças Pinto, Paulo Pimentel de Assumpção and Rommel Rodriguez Burbano
Funding Agency and Grant Number	Funding Agency Grant Number Conselho Nacional de Desenvolvimento Científico e Tecnológico 401976/2010-6 Conselho Nacional de Desenvolvimento Científico e Tecnológico 05220/2013-6 (to Burbano RR) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior PNPD 2810/2011 (to Moreira-Nunes CA)
Corresponding Author	Caroline Aquino Moreira-Nunes, PhD, Postdoctoral Reasearch Fellow, Biological Science Institute, Federal University of Para. Augusto Correa street 01, Belem 66075110, Brazil. -caroline@ufpa.br
Key Words	Familial adenomatous polyposis; APC; Torrent sequencing; Colorectal cancer
Core Tip	In the north region of Brazil, gastrointestinal tumors are the second most frequent type of cancer among men and the third most frequent among women. These tumors are considered a serious public health problem because they are often diagnosed in advanced stages and have extremely low survival rates. The evaluation of the family history to determine the number of relatives affected, and the genetic screening analysis are important for preventive measures to be taken to assist in the early diagnosis of patients who have not yet developed the disease, as in the case of some patients analyzed in this study.
Publish Date	2015-08-20 13:37
Citation	Moreira-Nunes CA, Alcântara DFA, Lima-Júnior SF, Cavalléro SRA, Rey JA, Pinto GR, Assumpção PP, Burbano RR. Presence of c.3956delC mutation in familial adenomatous polyposis patients from Brazil. World J Gastroenterol 2015; 21(31): 9413-9419
URL	http://www.wjgnet.com/1007-9327/full/v21/i31/9413.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i31.9413

Full Article (PDF)	WJG-21-9413.pdf
Full Article (Word)	WJG-21-9413.doc
Manuscript File	12764-Review.doc
Answering Reviewers	12764-Answering reviewers.pdf
Audio Core Tip	12764-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	12764-Conflict-of-interest statement.pdf
Copyright License Agreement	12764-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	Editing_Certificate_20140724205310.pdf
Peer-review Report	12764-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	12764-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	12764-Scientific misconduct check.pdf
Scientific Editor Work List	12764-Scientific editor work list.pdf