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Articles Published Processes
10/13/2026 9:29:21 AM | Browse: 2 | Download: 0
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Received |
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2026-09-04 03:18 |
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Peer-Review Started |
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2026-09-04 03:20 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-09-28 01:17 |
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Revised |
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2026-10-01 18:54 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-10-12 03:05 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-10-12 10:10 |
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Articles in Press |
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2026-10-12 10:10 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-10-13 01:55 |
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Publish the Manuscript Online |
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2026-10-13 09:29 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Correspondence |
| Article Title |
Letter to the Editor: Hepatocellular pattern is compatible with fenbendazole-associated drug-induced liver injury
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Arunkumar Krishnan and Tinsay A Woreta |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Arunkumar Krishnan, MD, Department of Medicine, Atrium Health Levine Cancer, 1021 Morehead Medical Dr, Charlotte, NC 28204, United States. dr.arunkumar.krishnan@gmail.com |
| Key Words |
Fenbendazole; Drug-induced liver injury; Hepatocellular injury; Immune checkpoint inhibitor; Roussel Uclaf Causality Assessment Method; Tumor onconecrosis |
| Core Tip |
Modest alkaline phosphatase elevation does not contradict hepatocellular drug-induced liver injury, and the aspartate aminotransferase:alanine aminotransferase ratio cannot establish tumor onconecrosis. Our original clinical assessment favored fenbendazole-associated injury on the overall course, with residual uncertainty from co-exposures. The reported R ratio and Roussel Uclaf Causality Assessment Method score remain unresolved verification needs rather than established errors; this limitation does not validate an alternative mechanism. Severe liver injury should prompt clinical evaluation and should not be interpreted as evidence of anticancer efficacy. |
| Publish Date |
2026-10-13 09:29 |
| Citation |
Krishnan A, Woreta TA. Letter to the Editor: Hepatocellular pattern is compatible with fenbendazole-associated drug-induced liver injury. World J Clin Cases 2026; 14(27): 127697
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| URL |
https://www.wjgnet.com/2307-8960/full/v14/i27/127697.htm |
| DOI |
https://doi.org/10.12998/wjcc.127697 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
