Publication Name	World Journal of Stem Cells
Manuscript ID	12783
Country	Japan

Received	2014-07-25 17:46
Peer-Review Started	2014-07-26 22:58
To Make the First Decision	2014-08-14 14:53
Return for Revision	2014-08-14 20:24
Revised	2014-08-29 14:18
Second Decision	2014-09-01 15:17
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-09-01 15:24
Articles in Press	2014-09-01 15:24
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-09-15 12:55
Publish the Manuscript Online	2014-09-25 12:31

ISSN	1948-0210 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Neurosciences
Manuscript Type	Minireviews
Article Title	Sox2 transcription network acts as a molecular switch to regulate properties of neural stem cells
Manuscript Source	Invited Manuscript
All Author List	Koji Shimozaki
Funding Agency and Grant Number	Funding Agency Grant Number Nagasaki ken Medical Association
Corresponding Author	Koji Shimozaki, PhD, Division of Functional Genomics, Center for Frontier Life Science, Nagasaki University, 1-12-4, Sakamoto, Nagasaki 852-8523, Japan. shimozak@nagasaki-u.ac.jp
Key Words	Neural stem cells; Self-renewal; Multipotency; Sox2; Transcriptional network
Core Tip	Neural stem cells (NSCs) are cells that are capable of both self-renewal and multipotency. In these two processes, the transcription factor Sox2 serves as a switch for the central molecular mechanism. Sox2 forms complexes with its partner factors to perform its transcription-related functions. This partner switching presumably serves as an important key to the intrinsic functions of NSCs. A detailed understanding of these molecular mechanisms will advance our understanding of basic neuroscience and increase the feasibility of employing cell reprogramming technology in regenerative medicine.
Publish Date	2014-09-25 12:31
Citation	Shimozaki K. Sox2 transcription network acts as a molecular switch to regulate properties of neural stem cells. World J Stem Cells 2014; 6(4): 485-490
URL	http://www.wjgnet.com/1948-0210/full/v6/i4/485.htm
DOI	http://dx.doi.org/10.4252/wjsc.v6.i4.485

Full Article (PDF)	WJSC-6-485.pdf
Full Article (Word)	WJSC-6-485.doc
Manuscript File	12783-Review.doc
Answering Reviewers	12783-Answering reviewers.pdf
Copyright License Agreement	12783-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	12783-Language certificate.pdf
Peer-review Report	12783-Peer review(s).pdf
Scientific Misconduct Check	12783-CrossCheck.jpg
Scientific Editor Work List	12783-Scientific editor work list.pdf