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1/14/2015 11:53:00 AM | Browse: 1020 | Download: 1401
Publication Name World Journal of Stem Cells
Manuscript ID 12804
Country Brazil
Received
2014-07-26 13:23
Peer-Review Started
2014-07-26 22:38
To Make the First Decision
2014-08-28 15:09
Return for Revision
2014-09-01 17:43
Revised
2014-09-22 04:17
Second Decision
2014-10-27 16:55
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-10-27 17:14
Articles in Press
2014-10-27 17:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-12-22 11:03
Publish the Manuscript Online
2015-01-14 11:53
ISSN 1948-0210 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Minireviews
Article Title Obesity and weight loss could alter the properties of adipose stem cells?
Manuscript Source Invited Manuscript
All Author List Leandra S Baptista, Karina R Silva and Radovan Borojevic
Funding Agency and Grant Number
Funding Agency Grant Number
Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Corresponding Author Leandra S Baptista, PhD, Laboratório de bioengenharia de tecidos, Instituto Nacional de Metrologia, Qualidade e Tecnologia (Inmetro), Av. Nossa Senhora das Graças, 50 - Xerém, Duque de Caxias 25250-020, Brazil. leandra.baptista@gmail.com
Key Words Adipose stem cells; Subcutaneousadipose tissue; Obesity; Weight loss; Regenerative medicine
Core Tip In this mini-review, we summarize recent aspects regarding obese subcutaneous adipose tissue with a focus in adipogenic and secretory capacities of adipose stem cells. In particular, we discuss how the occurrence of obesity and weight loss could alter the properties of stem cells and the consequences of using adipose-derived stem cells in regenerative medicine. Our previous results reveal that, after massive weight loss subsequent to bariatric surgery, stem cells retain an adipogenic memory besides a predominance of larger blood vessels in subcutaneous adipose tissue. Inflammatory subcutaneous adipose tissue microenvironment found in obese patients and even the massive weight loss could alter adipose tissue-derived stem cells phenotype to a non-healthy state.
Publish Date 2015-01-14 11:53
Citation Baptista LS, Silva KR, Borojevic R. Obesity and weight loss could alter the properties of adipose stem cells? World J Stem Cells 2015; 7(1): 165-173
URL http://www.wjgnet.com/1948-0210/full/v7/i1/165.htm
DOI http://dx.doi.org/10.4252/wjsc.v7.i1.165
Full Article (PDF) WJSC-7-1.pdf
Full Article (Word) WJSC-7-1.doc
Manuscript File 12804-Review.docx
Answering Reviewers 12804-Answering reviewers.pdf
Copyright License Agreement 12804-Copyright assignment.pdf
Institutional Review Board Approval Form or Document Ethics_Committee_20140726113017.pdf
Non-Native Speakers of English Editing Certificate 12804-Language certificate.pdf
Peer-review Report 12804-Peer review(s).pdf
Scientific Misconduct Check 12804-CrossCheck.jpg
Scientific Editor Work List 12804-Scientific editor work list.pdf