Publication Name	World Journal of Clinical Cases
Manuscript ID	12806
Country

Received	2014-07-26 22:36
Peer-Review Started	2014-07-27 22:57
To Make the First Decision	2014-08-28 15:09
Return for Revision	2014-09-01 17:35
Revised	2014-09-20 01:44
Second Decision	2014-10-29 17:50
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-10-29 18:47
Articles in Press	2014-10-29 18:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-01-21 18:03
Publish the Manuscript Online	2015-02-05 16:28

ISSN	2307-8960 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Otorhinolaryngology
Manuscript Type	Review
Article Title	Upper aerodigestive tract disorders and gastro-oesophageal reflux disease
Manuscript Source	Invited Manuscript
All Author List	Andrea Ciorba, Chiara Bianchini, Michele Zuolo and Carlo Vittorio Feo
Funding Agency and Grant Number
Corresponding Author	Andrea Ciorba, MD, PhD, ENT Department, University of Ferrara and S. Anna University Hospital, Via Aldo Moro 8, 44124 Ferrara, Italy. andrea.ciorba@unife.it
Key Words	Clinical management; Gastro-oesophageal reflux; Extraoesophageal disease; Upper aerodigestive tract disorders; Etiopathogenesis; Therapy
Core Tip	Despite a growing number of clinical evidences, the association between gastro-oesophageal reflux disease (GORD) and extraoesophageal manifestations still derives from uncontrolled studies on small groups of patients. The evidences in the literature to support the proton pump inhibitor treatment of respiratory symptoms associated with GORD, in the absence of typical symptoms of reflux (heartburn and regurgitation), are scanty. A specific diagnostic tool, of respiratory symptoms associated with GORD, is missing even if oesophageal 24-h pH monitoring has been recommended. Large and prospective studies to assess the successful outcome of antireflux therapy, as well as surgical therapy, are still missing.
Publish Date	2015-02-05 16:28
Citation	Ciorba A, Bianchini C, Zuolo M, Feo CV. Upper aerodigestive tract disorders and gastro-oesophageal reflux disease. World J Clin Cases 2015; 3(2): 102-111
URL	http://www.wjgnet.com/2307-8960/full/v3/i2/102.htm
DOI	http://dx.doi.org/10.12998/wjcc.v3.i2.102

Full Article (PDF)	WJCC-3-102.pdf
Full Article (Word)	WJCC-3-102.doc
Manuscript File	12806-Review.doc
Answering Reviewers	12806-Answering Reviewers.pdf
Copyright License Agreement	12806-Copyright assignment.pdf
Peer-review Report	12806-Peer review(s).pdf
Scientific Misconduct Check	12806-CrossCheck.jpg
Scientific Editor Work List	12806-Scientific editor work list.pdf