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Articles Published Processes
3/20/2015 10:48:00 AM | Browse: 991 | Download: 1190
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Received |
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2014-07-27 17:36 |
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Peer-Review Started |
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2014-07-28 08:28 |
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To Make the First Decision |
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2014-08-28 15:08 |
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Return for Revision |
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2014-09-01 17:13 |
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Revised |
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2014-09-17 13:20 |
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Second Decision |
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2014-10-29 17:50 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2014-10-29 18:48 |
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Articles in Press |
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2014-10-29 18:48 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2014-11-01 05:44 |
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Typeset the Manuscript |
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2015-02-06 16:08 |
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Publish the Manuscript Online |
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2015-03-20 10:47 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Ophthalmology |
| Manuscript Type |
Review |
| Article Title |
Importance of the stem cell microenvironment for ophthalmological cell-based therapy
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Peng-Xia Wan, Bo-Wen Wang and Zhi-Chong Wang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National High-tech R&D Program of China (863 Program) |
2012AA020507 |
| National Natural Science Foundation of China |
81200659 |
| National Natural Science Foundation of China |
81270971 |
| Guangdong Natural Science Foundation |
S2012010009113 |
| Fundamental Research Funds of State Key Laboratory of Ophthalmology of China |
2012PI05 |
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| Corresponding Author |
Zhi-Chong Wang, MD, PhD, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54 South Xianlie Road, Guangzhou 510060, Guangdong Province, China. wzc001@hotmail.com |
| Key Words |
Microenvironment; Niche; Stem cell; Cell-based therapy; Ocular diseases; Ophthalmology |
| Core Tip |
Cell therapy is a promising treatment for the diseases caused by cell degeneration or death. However, the transplanted cells often develop fibrosis or are absorbed and cannot survive long. It is not simply because of seed cells, but also due to the cell microenvironment. How to reconstruct the stem cell microenvironment and strengthen its combination with the transplanted cells is the key to successful cell therapy. We will discuss the importance of the stem cell microenvironment for cell-based therapy in ocular diseases and introduce the progress of cell therapy for ocular diseases. |
| Publish Date |
2015-03-20 10:47 |
| Citation |
Wan PX, Wang BW, Wang ZC. Importance of the stem cell microenvironment for ophthalmological cell-based therapy. World J Stem Cells 2015; 7(2): 448-460 |
| URL |
http://www.wjgnet.com/1948-0210/full/v7/i2/448.htm |
| DOI |
http://dx.doi.org/10.4252/wjsc.v7.i2.448 |
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