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1/14/2015 11:53:00 AM | Browse: 455 | Download: 753
Publication Name World Journal of Stem Cells
Manuscript ID 12880
Country/Territory South Korea
2014-07-29 10:46
Peer-Review Started
2014-07-29 17:27
To Make the First Decision
2014-08-14 14:33
Return for Revision
2014-08-18 11:52
2014-09-01 18:17
Second Decision
2014-10-16 15:22
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-10-16 16:07
Articles in Press
2014-10-16 16:07
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-12-19 09:34
Publish the Manuscript Online
2015-01-14 11:53
ISSN 1948-0210 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Neurosciences
Manuscript Type Review
Article Title Adult human neural stem cell therapeutics: Current developmental status and prospect
Manuscript Source Invited Manuscript
All Author List Hyun Nam, Kee-Hang Lee, Do-Hyun Nam and Kyeung Min Joo
Funding Agency and Grant Number
Funding Agency Grant Number
Korea Ministry of Food and Drug Safety in 2014 10172KFDA993
Corresponding author Kyeung Min Joo, MD, PhD, Department of Anatomy and Cell Biology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-Dong, Gangnam-gu, Seoul 135-710, South Korea. kmjoo@skku.edu
Keywords Adult neural stem cell; Neurological diseases; Stem cell therapy; Preclinical trial; Clinical trial
Core Tip In this review, we compare advantages and disadvantages of various types of stem cells for regenerative therapy in neurological disease, and discuss the preclinical and clinical developmental hurdles of stem cell technologies. While at present, adult neural stem cells (aNSCs) have clinical advantages, technical issues in the isolation and expansion of aNSCs prevent active preclinical and clinical applications of aNSCs. However, several papers have recently reported scientific breakthroughs, on the basis of which broad application trials using aNSCs could be performed. In this review, we also summarize the current status of preclinical and clinical applications of aNSCs for various neurological diseases.
Publish Date 2015-01-14 11:53
Citation Nam H, Lee KH, Nam DH, Joo KM. Adult human neural stem cell therapeutics: Current developmental status and prospect. World J Stem Cells 2015; 7(1): 126-136
Url http://www.wjgnet.com/1948-0210/full/v7/i1/126.htm
DOI http://dx.doi.org/10.4252/wjsc.v7.i1.126
Full Article (PDF) WJSC-7-126.pdf
Full Article (Word) WJSC-7-126.doc
Manuscript File 12880-Review.docx
Answering Reviewers 12880-Answering reviewers.pdf
Copyright License Agreement 12880-Copyright assignment.pdf
Peer-review Report 12880-Peer review(s).pdf
Scientific Misconduct Check 12880-CrossCheck.jpg
Scientific Editor Work List 12880-Scientific editor work list.pdf