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Articles Published Processes
1/14/2015 11:53:00 AM | Browse: 1204 | Download: 1700
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Received |
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2014-07-29 10:46 |
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Peer-Review Started |
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2014-07-29 17:27 |
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To Make the First Decision |
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2014-08-14 14:33 |
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Return for Revision |
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2014-08-18 11:52 |
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Revised |
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2014-09-01 18:17 |
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Second Decision |
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2014-10-16 15:22 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-10-16 16:07 |
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Articles in Press |
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2014-10-16 16:07 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-12-19 09:34 |
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Publish the Manuscript Online |
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2015-01-14 11:53 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Neurosciences |
| Manuscript Type |
Review |
| Article Title |
Adult human neural stem cell therapeutics: Current developmental status and prospect
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Hyun Nam, Kee-Hang Lee, Do-Hyun Nam and Kyeung Min Joo |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Korea Ministry of Food and Drug Safety in 2014 |
10172KFDA993 |
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| Corresponding Author |
Kyeung Min Joo, MD, PhD, Department of Anatomy and Cell Biology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-Dong, Gangnam-gu, Seoul 135-710, South Korea. kmjoo@skku.edu |
| Key Words |
Adult neural stem cell; Neurological diseases; Stem cell therapy; Preclinical trial; Clinical trial |
| Core Tip |
In this review, we compare advantages and disadvantages of various types of stem cells for regenerative therapy in neurological disease, and discuss the preclinical and clinical developmental hurdles of stem cell technologies. While at present, adult neural stem cells (aNSCs) have clinical advantages, technical issues in the isolation and expansion of aNSCs prevent active preclinical and clinical applications of aNSCs. However, several papers have recently reported scientific breakthroughs, on the basis of which broad application trials using aNSCs could be performed. In this review, we also summarize the current status of preclinical and clinical applications of aNSCs for various neurological diseases. |
| Publish Date |
2015-01-14 11:53 |
| Citation |
Nam H, Lee KH, Nam DH, Joo KM. Adult human neural stem cell therapeutics: Current developmental status and prospect. World J Stem Cells 2015; 7(1): 126-136 |
| URL |
http://www.wjgnet.com/1948-0210/full/v7/i1/126.htm |
| DOI |
http://dx.doi.org/10.4252/wjsc.v7.i1.126 |
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