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Articles Published Processes
1/14/2015 11:53:00 AM | Browse: 1126 | Download: 1601
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Received |
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2014-07-29 09:40 |
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Peer-Review Started |
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2014-07-30 08:53 |
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To Make the First Decision |
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2014-09-28 13:59 |
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Return for Revision |
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2014-09-29 18:44 |
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Revised |
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2014-10-14 01:16 |
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Second Decision |
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2014-10-29 18:03 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-10-29 18:57 |
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Articles in Press |
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2014-10-29 18:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-12-22 11:04 |
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Publish the Manuscript Online |
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2015-01-14 11:53 |
ISSN |
1948-0210 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Hematology |
Manuscript Type |
Review |
Article Title |
Identify multiple myeloma stem cells: Utopia?
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Manuscript Source |
Invited Manuscript |
All Author List |
Ilaria Saltarella, Aurelia Lamanuzzi, Antonia Reale, Angelo Vacca and Roberto Ria |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Associazione Italiana per la Ricerca sul Cancro, AIRC 5 × 1000 Molecular Clinical Oncology Special Program, Milan, IT |
9965 |
European Commission’s Seventh Framework Programme (EU FPT7) under grant agreement |
278706 (OVERMyR) |
MIUR PRIN 2010NECHBX |
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Corresponding Author |
Roberto Ria, MD, Department of Biomedical Sciences and Human Oncology, Section of Internal Medicine “G. Baccelli”, University of Bari “Aldo Moro” Medical School, Policlinico, Piazza Giulio Cesare, 11, I-70124 Bari,
Italy. roberto.ria@uniba.it
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Key Words |
Bone marrow microenvironment; Cancer stem cells; Multiple myeloma; Stem cells niche; Stemness |
Core Tip |
Multiple myeloma is a still incurable malignancy. Several study about multiple myeloma cancer stem cells showed their ability of self-renewal, survival and drug resistance. Besides, these cells are able to initiate and develop tumor when transferred into mice recipients. So understanding multiple myeloma cancer stem cells mechanisms become important to design new efficient targeting strategies for multiple myeloma. The aim of this review is to elucidate the state of art about multiple myeloma cancer stem cells and their critical role in maintenance of disease. |
Publish Date |
2015-01-14 11:53 |
Citation |
Saltarella I, Lamanuzzi A, Reale A, Vacca A, Ria R. Identify multiple myeloma stem cells: Utopia? World J Stem Cells 2015; 7(1): 84-95 |
URL |
http://www.wjgnet.com/1948-0210/full/v7/i1/84.htm |
DOI |
http://dx.doi.org/10.4252/wjsc.v7.i1.84 |
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