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5/20/2015 4:43:00 PM | Browse: 384 | Download: 459
Publication Name World Journal of Hepatology
Manuscript ID 12995
Country of Manuscript Source Spain
Received
2014-08-01 09:29
Peer-Review Started
2014-08-01 22:04
To Make the First Decision
2014-08-28 14:45
Return for Revision
2014-09-04 15:00
Revised
2015-01-31 22:48
Second Decision
2015-02-10 16:18
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-02-12 14:37
Articles in Press
2015-02-12 14:37
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-04-29 17:15
Publish the Manuscript Online
2015-05-20 16:43
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript Type Review
Article Title Bone changes in alcoholic liver disease
Manuscript Source Invited Manuscript
All Author List Emilio González-Reimers, Geraldine Quintero-Platt, Eva Rodríguez-Rodríguez, Antonio Martínez-Riera, Julio Alvisa-Negrín and Francisco Santolaria-Fernández
Funding Agency and Grant Number
Corresponding author Dr. Emilio González-Reimers, PhD, Servicio de Medicina Interna, Hospital Universitario de Canarias, Universidad de La Laguna, Ofra s/n, Tenerife, 38320 Canary Islands, Spain. egonrey@ull.es
Keywords Alcoholism; Liver disease; Osteoporosis; Vitamin D; Bone fractures
Core Tip Alcoholism is associated with an increased risk of fractures and a higher prevalence of bone disease, particularly osteoporosis. While ethanol has a direct toxic effect on bone, other factors such as malnutrition, increased levels of proinflammatory cytokines, alcoholic myopathy and neuropathy, and an increased risk of trauma also contribute to bone disease. It is noteworthy that alterations in bone metabolism have been described as reversible so that the mainstay of treatment should be alcohol abstinence. Treatment with vitamin D, calcium, and biphosphonates have been studied in the general population but further trials are needed in alcoholic patients.
Publish Date 2015-05-20 16:43
Citation González-Reimers E, Quintero-Platt G, Rodríguez-Rodríguez E, Martínez-Riera A, Alvisa-Negrín J, Santolaria-Fernández F. Bone changes in alcoholic liver disease. World J Hepatol 2015; 7(9): 1258-1264
Url http://www.wjgnet.com/1948-5182/full/v7/i9/1258.htm
DOI http://dx.doi.org/10.4254/wjh.v7.i9.1258
Full Article (PDF) WJH-7-1258.pdf
Full Article (Word) WJH-7-1258.doc
Manuscript File 12995-Review.doc
Answering Reviewers 12995-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form 12995-Conflict-of-interest statement.pdf
Copyright License Agreement 12995-Copyright assignment.pdf
Peer-review Report 12995-Peer-review(s).pdf
Scientific Misconduct Check 12995-Scientific misconduct check.pdf
Scientific Editor Work List 12995-Scientific editor work list.pdf